Failure to Thrive: Causes & Reasons

Possible Causes for Failure to Thrive

It presents with failure to thrive, nausea, and vomiting in children and is a common reason for dysphagia and food impaction in adults. [ncbi.nlm.nih.gov]

Dysphagia Chest or upper abdominal pain Food stuck in the esophagus Heartburn that doesn’t respond to medication Regurgitation In children: vomiting, poor weight gain or failure [nm.org]

EE Symptoms may include: Poor weight gain (failure to thrive) Refusal to eat Vomiting often occurring with meals Heartburn Difficulty swallowing (dysphagia) Pain or discomfort [eosinophilicesophagitishome.org]

Primary Immune Deficiency Disorder

Failure-to-thrive was a significant predictor of both neutrophil and T-lymphocyte-related PID. [medscape.com]

[…] to thrive/poor weight gain Autoimmune disorders such as lupus, rheumatoid arthritis or type 1 diabetes Blood problems such as low platelet counts or anemia How is Immune [lifespan.org]

Diarrhea, failure to thrive, opportunistic infections, and severe routine infections in a child younger than three months should raise suspicion for SCID. [aafp.org]

Component Complement 5 Deficiency

Blogs Submit your blog on Generalized Erythroderma, Diarrhea, And Failure To Thrive to be featured! [novusbio.com]

From Wikidata Jump to navigation Jump to search disease Erythroderma desquamativum Generalized erythroderma, diarrhea, and failure to thrive Erythroderma desquamativa of Leiner [wikidata.org]

[…] to thrive. [malacards.org]

Malabsorption Syndrome

Herein, we describe a 14-year-old girl who presented with anemia, failure to thrive, osteoporosis, zinc, and vitamin deficiency. [ncbi.nlm.nih.gov]

[…] to thrive Children Failure to Thrive (For Parents) Nemours Foundation Intestinal Failure (Short Bowel Syndrome) North American Society for Pediatric Gastroenterology, Hepatology [chcrr.org]

This is called failure to thrive. The child may not grow and develop normally. [nlm.nih.gov]

Congenital Vitamin B12 Deficiency

Failure to-thrive is also associated with IGS [8,9]. [ncbi.nlm.nih.gov]

[…] to thrive. [imagebank.hematology.org]

[…] to thrive, vomiting, diarrhea and developmental delay often with myelopathy or peripheral neuropathy. [treatable-id.org]

Congenital Bile Acid Synthesis Defect Type 2

Related symptoms: Growth delay Failure to thrive Muscle weakness Anemia Feeding difficulties SOURCES: OMIM ORPHANET MENDELIAN More info about BETA-THALASSEMIA Medium match [mendelian.co]

Affected infants show failure to thrive and secondary coagulopathy. [malacards.org]

Clinical features include failure to thrive, jaundice, steatorrhea, hepatomegaly, cirrhosis, rickets and splenomegaly. [preventiongenetics.com]

Leigh's Disease

These difficulties lead to decrease nutrition intake, which can exacerbate subsequent malnutrition or failure to thrive. [eyewiki.aao.org]

Early symptoms: Vomiting, diarrhoea, and problems with swallowing that leads to failure to thrive (inability/difficulty growing and gaining weight at the expected rate) in [ideas.org.au]

In addition, patients may develop optic atrophy.[5] Non-ocular systemic manifestations Patients often present with failure to thrive with psychomotor retardation and regression [eyewiki.aao.org]

Childhood Celiac Disease

Failure to thrive describes infants and children who don't gain weight or develop as quickly as their peers. [verywellhealth.com]

Failure to thrive/delayed growth or puberty – Failure to thrive is a term used to describe children who are far behind their peers in height and weight. [beyondceliac.org]

Failure to thrive/delayed growth or puberty - Failure to thrive is a term used to describe children who are far behind their peers in height and weight. [beyondceliac.org]

Alpers Syndrome

Mangalat, N, Tatevian, N, Bhattacharjee, MB & Rhoads, JM 2012, ' Alpers syndrome: An unusual etiology of failure to thrive ', Ultrastructural Pathology, vol. 36, no. 4, pp [uthealth.influuent.utsystem.edu]

The first symptoms of the disorder are usually nonspecific and may include hypoglycemia secondary to underlying liver disease, failure to thrive, infection-associated encephalopathy [ninds.nih.gov]

DIFFERENTIAL DIAGNOSIS The differential diagnosis of intractable epilepsy, developmental delay, and failure to thrive in infancy includes a broad range of metabolic and genetic [consultant360.com]

Eosinophilic Esophagitis

A 16-month-old boy presented with failure to thrive despite sufficient caloric intake, hypersalivation, abdominal pain, chronic diarrhea and blepharitis. [ncbi.nlm.nih.gov]

It presents with failure to thrive, nausea, and vomiting in children and is a common reason for dysphagia and food impaction in adults. [ncbi.nlm.nih.gov]

Infants and toddlers manifest with food refusal, vomiting, choking with meals and in rare cases, failure to thrive. [orpha.net]

Acrodermatitis Enteropathica

[…] to thrive Failure to thrive is also a common feature seen in acrodermatitis enteropathica. [4] Irritability Children are highly irritable. [explainmedicine.com]

Case1: Four-month-old male patient was admitted with diffuse skin eruptions, failure to thrive, edema, hypoalbuminemia and anemia.His sweat test was not diagnostic; but he [erj.ersjournals.com]

Associated symptoms include failure to thrive, growth retardation, muscle wasting, irritability, depression, and photophobia. [whonamedit.com]

Hereditary Fructose Intolerance

[…] to thrive, and renal and liver failure. [ncbi.nlm.nih.gov]

In the long run, these symptoms will lead to failure to thrive. [symptoma.com]

We describe a patient with failure to thrive, hepatomegaly, liver dysfunction, and elevation of multiple plasma lysosomal enzyme activities mimicking mucolipidosis II or III [ncbi.nlm.nih.gov]

Pierre Robin Syndrome

This failure to thrive was reversed in the infants managed with NP tubes in comparison with an age-matched groups nursed while prone. [ncbi.nlm.nih.gov]

Two patients then improved dramatically; whereas one continued with respiratory distress and failure to thrive and required tracheostomy. [ncbi.nlm.nih.gov]

Increased energy expenditure due to breathing efforts can lead to failure to thrive. [pedclerk.bsd.uchicago.edu]

Marasmus

Marasmus results from a lack of adequate calories and proteins and is seen in children with failure to thrive and in individuals in a state of starvation. [medical-dictionary.thefreedictionary.com]

See also: FAILURE TO THRIVE Bibliography Bennett, S. "Failure to Thrive." Paediatrics and Child Health 1(1996):206-210. Frongillo, Edward A. Protein-Energy Malnutrition. [encyclopedia.com]

Clinical findings Failure to thrive, weight loss, emaciation, decreased skin turgor, skin and muscle atrophy; children have a wizened appearance, are listless, have abdominal [medical-dictionary.thefreedictionary.com]

Beta Thalassaemia Major

Anemia and failure to thrive are characteristic features. [sideeffects.embl.de]

The rare disease is usually diagnosed in infancy with symptoms of severe anemia, failure to thrive and progressive pallor. [checkrare.com]

Children develop life-threatening anemia, have failure to thrive, and may develop jaundice. [secure.ssa.gov]

Farber Disease

Severe cognitive disability, failure to gain motor skills, failure to thrive, and joint contractures developed. [ncbi.nlm.nih.gov]

METHODS: Here we describe a 2-year-old female, a product of a non-consanguineous Emirati union, who was quite well until 8 months of age when presented with failure to thrive [ncbi.nlm.nih.gov]

The most severe neonatal form presents at birth with hydrops fetalis, lethargy, and failure to thrive, as well as hepatosplenomegaly, rapid neurological deterioration, and [orpha.net]

Congenital AIDS

RESULTS: 6 of the 9 children had diarrhea and failure to thrive all within the first 9 mo. of life. [nature.com]

These digestive problems can lead to failure to gain weight and grow at the expected rate (failure to thrive) and malnutrition. [ghr.nlm.nih.gov]

[…] to thrive Diagnosis ↓ IgG, IgA, IgE Normal or ↑ IgM Lymph node biopsy: absent germinal centers Treatment Ataxia telangiectasia See ataxia telangiectasia for details. [amboss.com]

Shwachman-Diamond Syndrome

Failure to thrive Failure to thrive may indicate exocrine pancreatic insufficiency (EPI), a condition that occurs when the pancreas fails to provide the necessary amount of [rarecare.world]

Exocrine pancreatic insufficiency results in failure to thrive, growth retardation, and chronic steatorrhea. [orpha.net]

As a result, they often have fatty, foul-smelling stools (steatorrhea); are slow to grow and gain weight (failure to thrive); and experience malnutrition. [malacards.org]

Glycogen Storage Disease Type 4

Morbidity is chiefly due to hepatosplenomegaly, hepatic failure and failure to thrive seen in affected individuals. [symptoma.com]

Such signs typically include failure to thrive – slow growth and failure to gain weight at the expected rate. There may be an abnormally large liver and spleen. [agsd.org.uk]

Symptoms of GSD 4 usually begin in infancy and typically include failure to thrive; enlarged liver and spleen (hepatosplenomegaly); and in many cases, progressive liver cirrhosis [diseaseinfosearch.org]

Wolman Disease

Patients with Wolman disease typically present during the first two months of life with failure to thrive, diarrhea and vomiting. [radiopaedia.org]

In infants, poor weight gain, massive hepatosplenomegaly, calcified adrenal glands (present about 2/3 of the time), vomiting, diarrhea and failure to thrive are indicative [ncbi.nlm.nih.gov]

This case reinforces that early onset LAL deficiency should be considered in a baby presenting with failure to thrive, gastrointestinal symptoms and hepatosplenomegaly. [casereports.bmj.com]

Fanconi-Bickel Syndrome

Therefore, clinicians in resource-poor settings should raise their index of suspicion for such metabolic disorders in settings with a high prevalence of failure to thrive [go.gale.com]

Mutations were also found in patients with atypical clinical signs such as intestinal malabsorption, failure to thrive, the absence of hepatomegaly, or renal hyperfiltration [ncbi.nlm.nih.gov]

5,6,7,8,9 Case Report: A 18 month old female child (Fig.1), second born of a non consanguineous marriage was brought to us with complains of failure to thrive, abdominal [journalofpediatriccriticalcare.com]

Progressive Familial Intrahepatic Cholestasis

This usually leads to failure to thrive, cirrhosis, and the need for liver transplantation. [en.wikipedia.org]

Patients usually present in early childhood with cholestasis, jaundice, and failure to thrive. [en.wikipedia.org]

Menkes Disease

MNK is characterized by loss of developmental milestones, hypotonia (floppy muscle tone), seizures, feeding difficulties, failure to thrive, subnormal body temperature, and [secure.ssa.gov]

Then symptoms begin, including floppy muscle tone, seizures, and failure to thrive. [ninds.nih.gov]

Affected patients are characterized by progressive hypotonia, seizures, failure to thrive and death in early childhood. [ncbi.nlm.nih.gov]

Congenital Disease

Some people have severe developmental delay, failure to thrive, and multiple organ problems, while others have diarrhea, low blood sugar ( hypoglycemia ), liver problems, [rarediseases.info.nih.gov]

Feeding difficulties leading to failure to thrive is also common. [rarediseases.org]

Failure to thrive is defined as the failure to grow and gain weight as would be expected based upon age and gender. [rarediseases.org]

Proximal Renal Tubular Acidosis

We think that low doses of alkali are useful in the transient form of proximal renal tubular acidosis to prevent bone lesions and failure to thrive. [ncbi.nlm.nih.gov]

Case Presentation A 2-month-old Caucasian female presented for failure to thrive. [pedsinreview.aappublications.org]

The disease results in deposition of crystals throughout the body; if untreated, it leads to failure to thrive, profound metabolic imbalance, early end-stage renal disease [doi.org]

Ventricular Septal Defect

[…] to thrive in infancy) Heart failure Infective endocarditis (bacterial infection of the heart) Pulmonary hypertension (high blood pressure in the lungs) leading to failure [nlm.nih.gov]

Indications for operation may be continued failure to thrive despite medication, or concern about high pressure in the pulmonary artery - pulmonary hypertension ( See Pulmonary [dhg.org.uk]

[…] ventricle from the aorta) Damage to the electrical conduction system of the heart during surgery (causing an irregular or slow heart rhythm) Delayed growth and development ( failure [nlm.nih.gov]

Niemann-Pick Disease

In type A NPD less than 5% or sphingomyelinase activity is observed and along with hepatosplenomegaly, patients display a failure to thrive, feeding problems, interstitial [symptoma.com]

thrive. [ncbi.nlm.nih.gov]

It is characterized by failure to thrive, hepatosplenomegaly, and a rapidly progressive neurodegenerative course culminating in death by 3 years of age. [ncbi.nlm.nih.gov]

Glycogen Storage Disease Type 1

PATIENTS: Two related children referred for failure to thrive, rickets, and hepatomegaly. [ncbi.nlm.nih.gov]

—Two related children referred for failure to thrive, rickets, and hepatomegaly. Intervention. —Dietary and therapeutic measures for rickets and renal tubular acidosis. [jamanetwork.com]

Pompe Disease

Affected infants may also fail to gain weight and grow at the expected rate (failure to thrive) and have breathing problems. [ghr.nlm.nih.gov]

It is characterized by a failure to thrive, cardiorespiratory difficulties and weakness with hypotonia, and leads to death within the first two years of life. [repub.eur.nl]

Infantile-onset disease is characterized by poor feeding and failure to thrive, hypotonia, and an enlarged heart. [sema4.com]

Glycogen Storage Disease Type 6

'The affected puppies showed a general failure to thrive, hypoglycemia (low blood sugar), mental depression, poor body condition and failure to nurse (symptoms of fading puppy [americanmaltese.org]

The classical clinical presentation for GSD IV is hepatomegaly with failure to thrive, followed by progressive liver failure and death by the age of 5 years. 1 Variable expression [adc.bmj.com]

[…] to thrive, life-threatening hypoglycemia and acidosis. [consultqd.clevelandclinic.org]