Hyperglycemia: Causes & Reasons

Possible Causes for Hyperglycemia

Epidemiology/Health Services/Psychosocial Research Abstract OBJECTIVE —Although postchallenge hyperglycemia is a well-established feature of type 2 diabetes, its association [doi.org]

Impairment of growth and susceptibility to certain infections may also accompany chronic hyperglycemia. [medscape.com]

Hyperglycemia develops when insulin secretion can no longer compensate for insulin resistance. [merck.com]

Diabetes Mellitus Type 2

This initial stage of the disease is marked by hyperglycemia and normoinsulinemia. [symptoma.com]

The opposite effect of uncontrolled hyperglycemia on adhesion molecules suggests different functions of VCAM-1 and ICAM-1 in complications of diabetes. [ncbi.nlm.nih.gov]

Hyperglycemia develops when insulin secretion can no longer compensate for insulin resistance. [msdmanuals.com]

Diabetes Mellitus Type 1

Abstract Diabetes mellitus (DM) is a group of metabolic disorders of carbohydrate metabolism in which glucose is underutilized, resulting in hyperglycemia. [ncbi.nlm.nih.gov]

Pathophysiology: Type 1 Diabetes Mellitus is a syndrome characterized by hyperglycemia and insulin deficiency resulting from the loss of beta cells in pancreatic islets (Mapes [u.osu.edu]

Chronic hyperglycemia impairs β-cell function. [cancertherapyadvisor.com]

Diabetes in Pregnancy

Discussion In 1952, Jorgen Pedersen 22 postulated that maternal hyperglycemia led to fetal hyperglycemia, which evoked an exaggerated fetal response to insulin. [content.nejm.org]

Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study: associations with neonatal anthropometrics. [care.diabetesjournals.org]

The Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study. Int J Gynaecol Obstet 2002 ;78: 69 - 77 17. [content.nejm.org]

Glucagonoma

Diagnosis Indications for Testing Pancreatic tumor Clinical symptoms of glucose intolerance, hyperglycemia, weight loss and cachexia, and migratory necrotic erythema rash [arupconsult.com]

Glucagonomas are rare functional endocrine tumors of the pancreas that classically present with symptoms of glucagon excess, including rash, hyperglycemia, diarrhea, and weight [ncbi.nlm.nih.gov]

[…] million people. we report a case of glucagonoma associated necrolytic migratory erythema in a male patient, 56 years, with signs of skin lesions mainly on his legs and groin, hyperglycemia [ncbi.nlm.nih.gov]

Diabetic Ketotic Coma

In people who have developed diabetes, glucose builds up in the blood, resulting in hyperglycemia. If it's not treated, hyperglycemia can cause serious health problems. [kidshealth.org]

Abstract The cases of three patients with focal seizure associated to non-cetotic hyperglycemia are reported. [ncbi.nlm.nih.gov]

An acute insulin deficiency and glycogenolysis, in conjunction with glyconeogenesis cause hyperglycemia. 1) Hyperglycemia leads to osmotic diuresis, leading to fluid volume [quizlet.com]

Total Parenteral Nutrition

CONCLUSIONS: Pre-parenteral glycemic values, diabetes and BMI values > 25 are predictors of hyperglycemia, so a early intervention to prevent and correct hyperglycemia may [ncbi.nlm.nih.gov]

Abstract Adverse outcomes have been associated with hyperglycemia in patients receiving total parenteral nutrition (TPN). [ncbi.nlm.nih.gov]

The aims of this study were to determine the prevalence in noncritically ill patients on TPN of diabetes, prediabetes, and stress hyperglycemia; the factors affecting hyperglycemia [ncbi.nlm.nih.gov]

Congenital Generalized Lipodystrophy

Improvement in the hyperglycemia, hyperinsulinemia and acanthosis nigricans was also observed. [ncbi.nlm.nih.gov]

The diagnosis is made on the basis of loss of body fat, muscular hypertrophy, acanthosis nigricans, hirsutism, hepatomegaly with fatty liver, hyperlipidemia and hyperglycemia [ncbi.nlm.nih.gov]

The diagnosis is made on the basis of lack of body fat, muscular hypertrophy, acanthosis nigricans, hirsutism, hepatomegaly with fatty liver, hyperlipidemia and hyperglycemia [ncbi.nlm.nih.gov]

Hypokalemia

KEYWORDS: Cushing syndrome; ectopic Cushing syndrome; hypercortisolism; hyperglycemia; hypokalemia; lung cancer; malignancy; weight loss [ncbi.nlm.nih.gov]

These perturbations include osmotic diarrhea, osmotic diuresis, and hyperinsulinemia secondary to hyperglycemia with resultant intracellular to cellular shifts in potassium [ncbi.nlm.nih.gov]

Laboratory data were significant for hypokalemia, hyperglycemia, and hyperlactatemia. [atsjournals.org]

Neonatal Diabetes Mellitus

ISSN 1695-4033, ISSN-e 1696-4608, Vol. 77, Nº. 5, 2012, pág. 344 Idioma: español Títulos paralelos: Diabetes mellitus: clinical presentation and differential diagnosis of hyperglycemia [dialnet.unirioja.es]

[…] for severe hyperglycemia, defined as glucose levels greater than 500 mg/dL. [ncbi.nlm.nih.gov]

All infants with persistent hyperglycemia should initially be started on an intravenous insulin infusion. [dovepress.com]

Pheochromocytoma

Blood tests revealed severe hyperglycemia (523 mg/dL) and metabolic acidosis (pH 7.21, anion gap 26.2 mEq/L, lactate 11.75 mmol/L) with a glycosylated hemoglobin level of [ncbi.nlm.nih.gov]

Google Scholar and PubMed were searched using the following key words: "diabetes," "pheochromocytoma," "adrenoreceptors," and "hyperglycemia." [ncbi.nlm.nih.gov]

Abstract Pheochromocytoma, a neuroendocrine tumor, is often associated with hyperglycemia. [ncbi.nlm.nih.gov]

Intravenous Hyperalimentation

[…] patients), subclavian vein thrombosis (one patient), sepsis in nine patients v none of the 62 control patients, fluid overload (27 patients), hyponatremia (25 patients), and hyperglycemia [ncbi.nlm.nih.gov]

[…] use strict aseptic technique, change solution and IV tubing every 24 hours, BG is monitored (at least 4x a day) and insulin administered per protocol; monitor for signs of hyperglycemia [quizlet.com]

Hyperglycemia can be avoided by monitoring blood glucose b. Hypoglycemia can be precipitated by suddenly discontinuing constant concentrated dextrose infusions. [openanesthesia.org]

Familial Partial Lipodystrophy

Findings include full and rounded face, xanthomata, acanthosis nigricans, and insulin-resistant hyperglycemia. [medical-dictionary.thefreedictionary.com]

CONCLUSION: Metreleptin replacement therapy is equally effective in FPLD patients with both SH and MH in reducing serum and hepatic triglyceride levels, but did not improve hyperglycemia [ncbi.nlm.nih.gov]

[…] hypoglycemia in diabetes Prevention and treatment of hypoglycemia in diabetes Perspective on hypoglycemia in diabetes Acknowledgments 34 Diabetic ketoacidosis Hyperosmolar hyperglycemia [books.google.com]

Glycogen Storage Disease Type 6

[…] case of liver glycogen synthase deficiency. ( 12794686 ) Laberge A.M....Lambert M. 2003 8 Glycogen synthase deficiency (glycogen storage disease type 0) presenting with hyperglycemia [malacards.org]

An oral glucose load causes mild hyperglycemia and hyperlactatemia. [clinicaladvisor.com]

Interestingly, recent studies have found that individuals with GSD VI do not always exhibit hyperglycemia with ketonemia. [3] Increased levels of urinary ketones and serum [emedicine.medscape.com]

Lipodystrophy

In a collaborative trial with the National Institutes of Health (NIH), we showed that leptin-replacement therapy was beneficial for improving hyperglycemia (increased levels [utsouthwestern.edu]

The administration of leptin or implantation of leptin-secreting adipose tissue was shown to result in alleviation of insulin resistance and hyperglycemia in rodents suffering [news-medical.net]

Acute Iron Poisoning

He had hyperglycemia and leukocytosis. [ncbi.nlm.nih.gov]

[…] iron damages mitochondria and causes lipid peroxidation, manifest mainly as renal and hepatic damage.Early signs of iron poisoning include vomiting and diarrhea, fever, hyperglycemia [usmleforum.com]

Blood test: HCT: 59, Hb 20, leukocytosis, hypertransaminasemia, hyperglycemia, acid-base status indicating normochloremic metabolic acidosis. [actagastro.org]

Cushing Syndrome

Typical clinical features include central obesity, thin, easily bruisable skin, abdominal striae, secondary hypertension, hyperglycemia, and proximal muscle weakness. [amboss.com]

A 59-year-old man presented with nasal congestion and neck swelling and was noted to have hypokalemia, hypertension, and hyperglycemia. [ncbi.nlm.nih.gov]

Reddening of the face, and/or acne High blood pressure (hypertension) Thinning of the skin, or skin that bruises easily Loss of bone density (osteoporosis) High blood sugar (hyperglycemia [dartmouth-hitchcock.org]

Subarachnoid Hemorrhage

∥Hyperglycemia was related to outcome in 409 patients. HG indicates hyperglycemia; NR, not reported. [oadoi.org]

In subanalysis, we explored if the strength of the association between hyperglycemia and outcome was affected by the cutoff value used to define hyperglycemia. [oadoi.org]

To generate a summary estimate of the unadjusted OR and the corresponding 95% CI for poor outcome in patients with hyperglycemia compared with patients with no hyperglycemia [oadoi.org]

Metabolic Disease

We also explore how dysregulation of autophagy leads to cell death in models of metabolic disease and its contributing factors-including nutrient state, hyperglycemia, dyslipidemia [ncbi.nlm.nih.gov]

Insulin resistance disrupts these pathways, resulting in hyperglycemia and dyslipidemia. [newswise.com]

Moreover, postprandial hyperglycemia in a patient with IFG denotes diabetes, a high-risk condition for CVD. [ahajournals.org]

Islet Cell Tumor

Although the patient initially had hyperglycemia due to diabetes mellitus, she conversely began to manifest hypoglycemic attacks 63 months postoperatively with the concomitant [ncbi.nlm.nih.gov]

[…] insulinoma Hypoglycemia, which causes fatigue, nervousness and shakiness, dizziness or lightheadedness, seizures, and fainting episodes Confusion Symptoms of a glucagonoma Hyperglycemia [cancer.net]

Cerebellar Hemorrhage

We aimed to determine the association of hyperglycemia on admission with 6-month functional outcome in CH patients. [ncbi.nlm.nih.gov]

Abstract Acute stroke patients commonly suffer from hyperglycemia. [ncbi.nlm.nih.gov]

Hyperglycemia (BS ≥ 140 mg/dl) was recently proved an independent predictor of poor outcome of CH [ 25 ]. [journals.plos.org]

Acquired Partial Lipodystrophy

Whereas the intensity of hyperglycemia is usually extreme, the duration of the hyperglycemia is variable, and this perhaps is the reason that DN is not seen in this group [cjasn.asnjournals.org]

The administration of leptin or implantation of leptin-secreting adipose tissue was shown to result in alleviation of insulin resistance and hyperglycemia in rodents suffering [news-medical.net]

[…] adipose tissue in maintenance of normal glucose and lipid homeostasis, and not surprisingly, adipose tissue transplantation in lipodystrophic mice has been shown to ameliorate hyperglycemia [mayoclinic.org]

Pituitary Cushing Syndrome

Hyperglycemia-related AEs occurred in 40.0 % of patients with acromegaly treated with pasireotide SC, and 10.0 % discontinued treatment because of hyperglycemia. [ncbi.nlm.nih.gov]

Pasireotide has a safety profile similar to other somatostatin analogues with the exception of hyperglycemia. [ncbi.nlm.nih.gov]

Overall, 118 of 162 patients (73%) had a hyperglycemia-related adverse event; 6% of patients discontinued treatment because of a hyperglycemia-related adverse event. [nejm.org]

Chronic Kidney Insufficiency

Hyperglycemia and AGE: Hyperglycemia and AGE directly induce mesangial matrix production, cellular expansion and apoptosis. [pathophys.org]

In summary, the majority of drugs available to treat hyperglycemia, and especially first-generation sulfonylureas and α-glucosidase inhibitors, are affected by kidney function [clinical.diabetesjournals.org]

In particular, controlling hyperglycemia in patients with diabetic nephropathy and controlling hypertension in all patients substantially slows deterioration of GFR. [merckmanuals.com]

Status Epilepticus

Although hyperglycemia is an important cause of acute symptomatic seizure (ASS), patients with ketotic hyperglycemia develop ASS less frequently. [ncbi.nlm.nih.gov]

[…] most common in older adults) brain malignancy intracranial bleed head trauma arteriovenous malformations Infections meningitis encephalitis Metabolic abnormalities hypo- or hyperglycemia [step2.medbullets.com]

These changes can be defined by the onset of tachycardia, hyperglycemia and or cardiac arrhythmias. [symptoma.com]

Wolfram Syndrome

Typically, WFS necessitates insulin treatment similar to type 1 diabetes (T1D), but the mechanism of beta cell mass reduction leading to hyperglycemia is different. [ncbi.nlm.nih.gov]

This is an intriguing finding because hyperglycemia occurs on top of tissue ER stress in Wolfram syndrome. [care.diabetesjournals.org]

Because additional Wolfram syndrome symptoms are more likely to develop in patients with poor glycemic control, hyperglycemia may be involved as well. [care.diabetesjournals.org]

Third Trimester Pregnancy

This is to find albumin, a protein that may indicate pre-eclampsia or toxemia, and glucose, which may indicate hyperglycemia. [hopkinsmedicine.org]

[…] discomforts Mother's weight Mother's blood pressure Urine test - to detect albumin (a protein) which may indicate preeclampsia or toxemia, and sugar (which may indicate hyperglycemia [stanfordchildrens.org]

Rate Monitor Hernia Hiking Hip Injury Hip Replacement Hip Training Hiring HIV/AIDS Holistic Health Hormones Horseback Riding Human Learning Hydration Hydrotherapy Hygiene Hyperglycemia [ptonthenet.com]

Paraneoplastic Syndrome

Refractory hyperglycemia may be due to glucagon-producing pancreatic tumors. [msdmanuals.com]

Refractory hyperglycemia may be due to glucagon -producing pancreatic tumors. [merckmanuals.com]

The clinical symptoms have a rapid onset and are generally accompanied by hypokalemia and hyperglycemia. [intechopen.com]

Acromegaly

In addition, we assessed the relation between insulin secretion and pasireotide-induced hyperglycemia. [ncbi.nlm.nih.gov]

Excess GH: 1) stimulates gluconeogenesis and lipolysis, causing hyperglycemia and elevated free fatty acid levels; 2) leads to both hepatic and peripheral insulin resistance [hopkinsguides.com]

Organophosphate Poisoning

Acute complications included fits in 50 (16.66) bradycardia in 30 (10%) and hyperglycemia in 15 (5%) patients. [ncbi.nlm.nih.gov]

These include: metabolic disorders, such as hyperglycemia (high blood sugar) and glycosuria (excess sugar in urine) diabetic ketoacidosis, in which your blood produces excess [healthline.com]

[…] and abdominal pain may be some of the first symptoms to occur after organophosphate exposure Genitourinary and/or endocrine effects: Urinary incontinence, hypoglycemia, or hyperglycemia [emedicine.medscape.com]