[…] of scrotum Lymphedema of uncertain etiology Lymphedema of vulva Lymphedema praecox Lymphedema, after surgery Lymphedema, limb Lymphedema, lower extremity Lymphedematous hyperkeratosis
Hyperkeratosis and papillomas may also be seen in someone with lymphedema. Hyperkeratosis is an overgrowth of the skin like a very thick callus.
Stage III lymphedema is characterized by a tremendous increase in volume, hardening of the dermal tissues, hyperkeratosis, and papillomas of the skin.
A biopsy was performed, and histologic analysis revealed acanthosis and papillomatosis, hyperkeratosis, increased dermal pigmentation, and a dermal lymphohistiocytic infiltrate
Abstract Acanthosis nigricans is a mucocutaneous dermatosis characterized by hyperpigmentation and a velvety papillomatous hyperkeratosis.
Acanthosis nigricans (AN) is a skin disorder characterized by focal or diffuse hyperkeratosis symmetric hyperpigmentation of the skin and oral cavity mucosa.
Abstract To elucidate the pathogenesis of impaired barrier function and the influence of surfactant on the stratum corneum in hyperkeratosis, we investigated morphological
Hence, this type of hyperkeratosis can be distinguished from other types of inherited palmoplantar keratosis.
Abstract Ichthyosis vulgaris is an autosomal dominant disorder of keratinization characterized by mild hyperkeratosis and reduced or absent keratohyalin granules in the epidermis
Skin hyperkeratosis and pigmentation and arthritis are also relatively uncommon.
The features in favour of AK were parakeratosis, hyperkeratosis, more severe keratinocyte pleomorphism and architectural disruption, and the presence of epidermal inflammatory
Validation of the AK-FAS showed good reproducibility for AK area and hyperkeratosis, even for dermatologists untrained on use of the scale.
Hyperkeratosis represents the most important limitation in the evaluation of squamous neoplasia as it may impair the analysis of deeper epidermal and dermal structures significantly
[…] cells Can be an advanced form of mycosis fungoides or arise de novo Characteristic triad of symptoms Systemic skin lesions Erythroderma accompanied by palmar and plantar hyperkeratosis
Case 1 A male patient, aged 30 years, was admitted to our Department with extremely itchy erythroderma with generalized peripheral lymphadenopathy and hyperkeratosis of the
Ichthyosiform MF has similar histopathologic findings to classic MF combined with features of ichthyosis, such as hypogranulosis and hyperkeratosis.25 The detection of features
The infection was characterised clinically by yellowish pigmentation of the nail plate and mild nail bed hyperkeratosis of the first left toe.
The infection was characterized clinically by yellow-brown discoloration of the nail plate, distal-lateral onycholysis and subungual hyperkeratosis of the first left toenail
If less than 2 mm of hyperkeratosis is present, no points are awarded.
Abstract Characteristics of alcoholic neuropathy have been obscured by difficulty in isolating them from features of thiamine-deficiency neuropathy. We assessed 64 patients with alcoholic neuropathy including subgroups without (ALN) and with (ALN-TD) coexisting thiamine deficiency. Thirty-two patients with[…]
[…] is hyperkeratosis of the sole of the foot.
Some types of hyperkeratosis are inherited conditions. They may be present at birth. Other kinds of hyperkeratosis may be early signs of skin cancer.
[…] often, hyperkeratosis develops on skin that has not been irritated.
[…] differentiation of keratinocytes and parakeratosis; lesions characteristically affect extensor surfaces, scalp and trunk; nails become dystrophic, showing onycholysis, subungual hyperkeratosis
Palmoplantar pustulosis: The characterizing feature of this variety is hyperkeratosis and clusters of sterile, yellow pustules on a background of erythema and scaling, affecting
Examination revealed dystrophic nails manifested by subungual hyperkeratosis and pustules, yellowish discolouration, and onycholysis, and the dorsal tongue was oedematous
What is Hyperkeratosis? Hyperkeratosis is a layered buildup of keratinized cell tissue and is distinctive for its leaf-like appearance.
Histopathology of leukoplakia can disclose hyperkeratosis with dysplasia or carcinoma or hyperkeratosis or parakeratosis without dysplasia.
PVL generally presents as a simple benign form of hyperkeratosis that tends to spread and become diffuse.
We observed invagination of basket-weave hyperkeratosis through the epidermis.
The histologic findings include papillomatosis, hyperkeratosis, and minimal or no acanthosis.
Histopathologically, hyperkeratosis, decreased granular layer, irregular papillomatosis, and hypermelanosis of the basal layer were present.
0 ratings Abstract: We report a rare genetic condition characterized by gingival hyperkeratosis with skin changes affecting the hands and feet.
We present a case of focal acral hyperkeratosis in a 9‐year‐old girl.
Clinical relevance: To inform clinicians of both the intra-oral and extra-oral features of focal palmoplantar and gingival hyperkeratosis.
Patients may also present with malodorous hyperhidrosis, follicular hyperkeratosis, nail dystrophy or dural calcifications.
Keywords: Papillon-Lefèvre Syndrome, Periodontitis, Palmoplantar, Hyperkeratosis, Cathepsin C 1.
Pa·pil·lon-Le·fèv·re syn·drome ( pah-pē-on[h]' le-fĕv ), [MIM*245000] a congenital hyperkeratosis of the palms and soles, with progessive destruction of alveolar bone about
On examination, diffuse hyperkeratosis of the palms and soles was observed (Figure 1 a, b) However, there was no extension of this hyperkeratosis to the dorsal aspects of
These findings suggested an association between internal malignancy and palmoplantar hyperkeratosis.
Fig. 2 Hyperkeratosis sparing the arches of feet.
ESOPHAGEAL CANCER Palmoplantar Keratoderma With Esophageal Cancer TOC Keratosis palmaris et plantaris with esophageal cancer TYLOSIS WITH ESOPHAGEAL CANCER; TOC Palmoplantar hyperkeratosis-esophageal
Symptoms and Signs Some symptoms of Howel-Evans syndrome include hyperkeratosis of palms, hyperkeratosis of the soles of the feet, and esophageal cancer.
Potential Signs and Symptoms Some symptoms of Howel-Evans syndrome consist of hyperkeratosis of palms, hyperkeratosis of the soles of the feet, and esophageal cancer.
Hidrotic ectodermal dysplasia is a rare genodermatosis with clinical hallmarks of alopecia, nail dystrophy, and palmoplantar hyperkeratosis.
Clouston's syndrome is an ectodermal dysplasia characterized by dystrophic nails, alopecia, and palmoplantar hyperkeratosis.
Medical treatment includes use of emollients and topical keratolytics (urea or lactic acid based) for softening of the nail plates and palmoplantar hyperkeratosis, topical
Acanthosis nigricans (AN) is a velvety and papillomatous pigmented hyperkeratosis of the skin, which has been recognized in some genetic disorders more severe than HCH involving
Moreover, insulin resistance and the appearance of acanthosis nigricans, a papillomatous pigmented hyperkeratosis of the skin appearing on the flexures of the neck in most
AN is a velvety and papillomatous pigmented hyperkeratosis of the skin, which appears mainly on the flexures and neck.
This patient also had hyperkeratosis of the palms and soles and involvement of the face.
Others have noted epidermal necrosis with or without blister formation; vacuolar degeneration of the basal layer; and psoriatic changes with acanthosis, papillomatosis, hyperkeratosis
Histopathology mostly showed hyperkeratosis, acanthosis, prominent granular layer, spongiosis and dermal infiltrate.
Fifteen patients had lichen sclerosus with various degrees of hyperkeratosis, while one had human papillomavirus-associated vulvar intraepithelial neoplasia and another had
[…] or parakeratosis Nuclear atypia not seen Microscopic (histologic) images Images hosted on other servers : Mild hyperkeratosis Epithelial thickening Chronic inflammatory cell
Eczematous inflammation or hyperkeratosis may be present. Prevalence: Common, 40% to 45% of non-neoplastic epithelial disorders.
The type of lesion varied from discrete macules with no or slight hyperkeratosis to confluent, protruding verrucous plaques.
Angiokeratomas are relatively rare vascular lesions characterized by ectasias of the papillary dermal blood vessels with secondary epidermal changes in the form of acanthosis and/or hyperkeratosis
It is characterized by vascular ectasia with overlying epidermal hyperkeratosis. The systemic form of angiokeratoma is associated with Fabry disease and fucosidosis.
The patient's skin disease was more remarkable for its hyperpigmentation than its hyperkeratosis.
Squames / scales Pathophysiology genetic disorders / keratinocyte genetic disorders / palmoplantar keratoderma Symptoms Burning, Diagnosis hyperkeratosis palmaris et plantaris
Histology of plantar skin revealed compact hyperkeratosis and irregular epidermal hyperplasia. Mycosis was excluded histologically.
Approximately 1 month after thallium exposure, Mees lines (transverse white lines on the nails) appear in the nail plate.  Other dermatologic findings include well-demarcated hyperkeratosis
Skin and nail symptoms include hardened patches of skin (hyperkeratosis) with unusually deep creases on the palms of the hands and the soles of the feet, unusual darkening
Histopathologic findings from three skin regions revealed characteristic features of epidermolytic hyperkeratosis, verruca vulgaris, and disseminated superficial porokeratosis
Microscopic Features:  Hyperkeratosis (more keratin - thick stratum corneum) - in "columns"; keratin in separate towers - not a flat thick sheet.
LM papillomatous hyperplasia (rete ridges long & curve inward), hyperkeratosis, hypergranulosis, large blood vessels at the dermal-epidermal junction, /-viral changes - perinuclear
[…] is hyperkeratosis of the sole of the foot.
Patient case no. 2022 Date added 18 May 2003 Patient details Age --Undetermined-- Localisation Upper limbs / hands / palms Description Primary Lesions Papule / hyperpigmented Hyperkeratosis
Oral retinoids may be helpful in reducing hyperkeratosis secondary to chronic arsenicism.
Keratosis pilaris (KP) is a common inherited disorder of follicular hyperkeratosis It is characterized by small, folliculocentric keratotic papules that may have surrounding
Abstract Folliculitis spinulosa decalvans is an uncommon condition characterized by follicular hyperkeratosis, followed by scarring alopecia.
BACKGROUND: Keratosis pilaris atrophicans defines a group of cutaneous disorders characterized by follicular hyperkeratosis and scarring.
Criteria evaluated included hyperkeratosis, epidermal atrophy, follicular plugging, basal cell vacuolation, vascular ectasia, hyalinosis, inflammatory infiltrate, dermal edema
A punch biopsy from an atrophic plaque was performed, and it revealed hyperkeratosis, atrophic epidermis, basal layer vacuolar degeneration, mild lymphocytic infiltration
Hyperkeratosis, epidermal atrophy, a swollen dermal collagen bundle, and prominent edema was evident (B) (H&E, original magnification 200).
[…] little or no hyperkeratosis.
Histological findings of orthokeratotic hyperkeratosis and acanthosis confirm our diagnosis.
[…] of the distal nails and focal palmoplantar hyperkeratosis.
Citation: Higgins E, Capra M, Schwartz ME, Smith FJD, McLean WHI, Irvine AD, Resolution of the plantar hyperkeratosis of pachyonychia congenita during chemotherapy for Ewing
A 28-year-old woman developed subungual hyperkeratosis of all toe-nails and thumb-nails associated with pain on pressure and walking.
Patients with Jadassohn-Lewandowsky Syndrome (MIM #167200; PC-1) have nail defects (onchyogryposis), palmoplantar hyperkeratosis, follicular hyperkeratosis and oral leukokeratosis
Electron microscopy demonstrated the features of epidermolytic hyperkeratosis. 3 From the differential diagnostic point of view, the mucosa hyperkeratosis syndrome has to
Fig. 3 Compact hyperkeratosis with parakeratosis, acanthosis, and prominent epidermolytic hyperkeratosis (hematoxylin and eosin stain).
Histopathology examination of Follicular keratotic papule showed follicular plugging, hyperkeratosis and acanthosis.