Hyperthermia: Causes & Reasons

Possible Causes for Hyperthermia

[…] onset; duration several hours “Crank” “Ecstasy” (3,4-methylenedioxymethamphetamine, MDMA, XTC, E, Molly): Often used at dances and “rave” parties Dehydration can lead to hyperthermia [emergency.unboundmedicine.com]

In addition, animal studies suggest that haloperidol can antagonize amphetamine-induced hyperthermia. [emedicine.medscape.com]

Toxicity is managed with supportive care, including IV benzodiazepines (for agitation, hypertension, and seizures) and cooling techniques (for hyperthermia). [merckmanuals.com]

Malignant Catatonia

Key Words Hyperthermia heatstroke neuroleptics lethal catatonia neuroleptic malignant syndrome malignant hyperthermia This is a preview of subscription content, log in to [link.springer.com]

Malignant catatonia (MC) is a disorder consisting of catatonic symptoms, hyperthermia, autonomic instability, and altered mental status. [ncbi.nlm.nih.gov]

Differential Diagnosis of catatonia Locked-in syndrome Seizures Malignant hyperthermia Parkinsonism Deception syndromes: What is Malignant hyperthermia occurs post-operatively [quizlet.com]

Salicylate Poisoning

[…] dosage Clinical effects <150mg/kg Minimal symptoms 150-300mg/kg Mild-moderate symptoms: Tinnitus, vomiting, hyperventilation >300mg/kg Severe symptoms: Acidosis, seizures, hyperthermia [rch.org.au]

Salicylate dosage Clinical effects Minimal symptoms 150-300mg/kg Mild-moderate symptoms: Tinnitus, vomiting, hyperventilation >300mg/kg Severe symptoms: Acidosis, seizures, hyperthermia [rch.org.au]

On admission, hyperthermia was aggravated by antipyretics. [e-jnc.org]

Tricyclic Antidepressant Overdose

The possible mechanisms of refractory hyperthermia are discussed. [link.springer.com]

Clinical presentation of overdose from the tricyclic agents includes cardiac arrhythmias, hypotension, seizures, coma and anticholinergic signs such as hyperthermia, flushing [ncbi.nlm.nih.gov]

Seizures, rhabdomyolysis, myocardial infarction, cardiac arrest, hyperthermia Cooling, sedation with benzodiazepines, hydration Toxidrome Drug Common Findings Other signs [academic.oup.com]

Thyrotoxic Crisis

We suggest the same dosage regimen as is used in the treatment of malignant hyperthermia. [ncbi.nlm.nih.gov]

Classic presentation characterized by signs and Carroll including: [5] Severe tachycardia Elevated blood pressure Heart failure Peripheral edema Pulmonary edema Chest pain Hyperthermia [physio-pedia.com]

Definition Signs of malignant hyperthermia include increased CO2 production or minute ventilation, increased O2 consumption, increased cardiac output, increased HR, increased [openanesthesia.org]

Monoamine Oxidase Inhibitor Poisoning

Death may result from hyperthermia which may peak as late as 24 hours after presentation. [inchem.org]

Signs of moderate disease include altered mental status, tachypnea, vomiting, dysrhythmias, hyperthermia, and hypertension. [ncbi.nlm.nih.gov]

Initial findings of excessive neuromuscular activity were followed by severe hyperthermia, coma, cardiovascular collapse, acute renal failure, hemolysis, rhabdomyolysis, and [ncbi.nlm.nih.gov]

Alcohol Withdrawal Delirium

[…] increased activity of these excitatory neuroreceptors, resulting in the clinical manifestations of ethanol withdrawal: tremors, agitation, hallucinations, seizures, tachycardia, hyperthermia [emedicine.medscape.com]

Anti-NMDA Receptor Encephalitis

Keywords: NMDA, receptor, autoimmune, synapse, paraneoplastic, schizophrenia, paraneoplastic disorder, neurologic symptoms, hyperthermia, hypoventilation, hypersexuality, [dx.doi.org]

Tachycardia and bradycardia, blood pressure lability, hyperthermia, hypoventilation, and/or apnea were each reported in most patients with autonomic instability. [ncbi.nlm.nih.gov]

M 29 66 12 Pacific Islander Mental status changes Choreoathetoid movements Tachycardia, hypertension, hyperthermia Y N Unk Y 8 N 170 (92%L, 2%M) Abnormal; dural and meningeal [ncbi.nlm.nih.gov]

Hyoscyamus Niger Poisoning

Cooling via evaporative methods is generally sufficient if hyperthermia is present. [calpoison.org]

Acute poisoning Stage of early stimulation: Euphoria, excitement, mydriasis, increased HR, BP, RR Stage of advanced stimulation: Vomiting, muscle twitching, dyspnoea, hyperthermia [slideshare.net]

Treatment is primarily supportive care, to maintain hydration and to treat hyperthermia with external cooling. [calpoison.org]

Subacute Sclerosing Panencephalitis

In the final phases, hypothalamic involvement may cause intermittent hyperthermia, diaphoresis, and pulse and blood pressure disturbances. [msdmanuals.com]

The symptoms of SSPE can include the following: Coma Death Seizures Irritability Dementia Blindness Spasticity Memory loss Optic atrophy Hyperthermia Unsteady gait Abnormal [disabled-world.com]

Anticholinergic Syndrome

Frampton A, Spinks J: Hyperthermia associated with central anticholinergic syndrome caused by a transdermal hyoscine patch in a child with cerebral palsy. [accessmedicina.mhmedical.com]

Dimethindene Maleate Poisoning

Treat coma (See Coma and stupor), seizures (See Seizures), hyperthermia (See Hyperthermia), and atypical ventricular tachycardia (See Circulation) if they occur. [accessmedicine.mhmedical.com]

Convulsions, rhabdomyolysis, and hyperthermia may occur with a serious overdose, and complications such as renal failure and pancreatitis have been reported. [accessmedicine.mhmedical.com]

Datura Stramonium

A cooling blanket can be used for hyperthermia. The patient may require bladder catheterization for urinary retention. [erowid.org]

[…] produces effects similar to that of an anticholinergic delirium: a complete inability to differentiate reality from fantasy (frank delirium, as contrasted to hallucination); hyperthermia [springerlink.com]

Elevated aspartate aminotransferase, LDH, bilirubin and prothrombin time have been reported, possibly secondary to muscle breakdown from seizures, increased tone and hyperthermia [erowid.org]

Neonatal Meningitis

[…] vomiting diarrhea abdominal distention (increase in abdominal size) neck rigidity cyanosis jaundice sunset eyes (downward gaze of the eyes) abnormal body temperature (hypo-or hyperthermia [en.wikipedia.org]

[…] diarrhea abdominal distention (increase in abdominal size) neck rigidity cyanosis jaundice and sunset eyes (downward gaze of the eyes) abnormal body temperature ( hypo -or hyperthermia [en.m.wikipedia.org]

Hyperammonemia Type 3

[…] in late infancy or childhood, except arginase deficiency, which is neonatal Clinical Accumulation of urea precursors–eg, ammonia, glutamine causes progressive lethargy, hyperthermia [medical-dictionary.thefreedictionary.com]

On the night following the surgery, he became confused and combative, with tachycardia, 106° hyperthermia, and generalized tonic-clonic seizures that the local hospital was [nucdf.org]

Tranylcypromine

Hyperthermia and its possible causative mechanisms and treatments are discussed. [ncbi.nlm.nih.gov]

Manifestations included and altered mental status that progressed to hyperthermia and coma. She recovered quickly and without complications. [ncbi.nlm.nih.gov]

We report the case of a 56-year old woman who developed a neurotoxic syndrome with coma, hyperthermia, muscular rigidity, myoclonic jerks and tachycardia following an intoxication [ncbi.nlm.nih.gov]

Parkinson Disease

Methamphetamine-induced hyperthermia and dopaminergic neurotoxicity in mice: Pharmacological profile of protective and nonprotective agents. [ncbi.nlm.nih.gov]

Poisoning

[…] quantification using Taqman real-time PCR assay demonstrated higher expression of IL-1β, TNF-α and iNOS, and lower expression of Nrf2 in methamphetamine intoxication and hyperthermia [ncbi.nlm.nih.gov]

Paracetamol was allegedly being given to treat hyperthermia ( n = 2). Benzodiazepines were detected in children who had received diazepam to stop seizures. [pediatrics.aappublications.org]

Aromatic L-Amino Acid Decarboxylase Deficiency

Sustained oculogyric crisis, or even status dystonicus, is potentially life threatening, with hyperthermia and rhabdomyolysis as major complications (44; 33). [medlink.com]

Furthermore, hyperthermia in AADCD can be due to autonomic temperature dysregulation and may not always represent a fever due to underlying infection. [ojrd.biomedcentral.com]

Venlafaxine

Serotonin syndrome is characterized by rapid development of hyperthermia, hypertension, myoclonus, rigidity, autonomic instability, mental status changes (e.g., delirium or [pdr.net]

Of the 7 deaths, 4 people had significant hyperthermia. There was a statistically significant increased risk of death associated with stimulant exposure. [ncbi.nlm.nih.gov]

Hyperthermia associated with drug intoxication. Crit Care Med. 1986 Nov; 14(11): 964–9. [doi.org]

Atropa Belladonna Poisoning

These convulsions can lead to hyperthermia, exhaustion, and oxygen depletion that eventually leads to asphyxiation. [medicaldaily.com]

Fluoxetine

The clinical features included coma, mydriasis, hyperthermia, tremor, hyperreflexia, rhabdomyolysis, renal failure and respiratory insufficiency. [ncbi.nlm.nih.gov]

Fenfluramine-induced hyperthermia and stimulation in the rabbit. [doi.org]

• MAO inhibitors: Potential for severe reaction when used with MAO inhibitors; autonomic instability, coma, death, delirium, diaphoresis, hyperthermia, mental status changes [web.archive.org]

Crack Ingestion

Signs of intoxication were hypertension, tachycardia, hyperthermia, agitation, and generalized seizure activity. [ncbi.nlm.nih.gov]

His illness included status epilepticus, wide and narrow complex bradyarrhythmias, ventricular arrhythmias, and delayed hyperthermia. [ncbi.nlm.nih.gov]

Rhabdomyolysis

[…] features, including hyperthermia, muscle rigidity, tachycardia, and elevated serum creatine kinase. [ncbi.nlm.nih.gov]

Abstract Anesthesia-induced rhabdomyolysis and malignant hyperthermia occur in response to the same agents and present with similar clinical features. [ncbi.nlm.nih.gov]

[…] cease trigger, give dantrolene Cool if hyperthermia (e.g. [lifeinthefastlane.com]

Hyperpyrexia

Hyperthermia. N Engl J Med 1993;329:483. [medtextfree.wordpress.com]

TO, 1, MHS1, hyperthermia of anesthesia, anesthesia related hyperthermia, malignant hyperthermia due to anesthesia (diagnosis), malignant hyperthermia, malignant hyperthermia [fpnotebook.com]

What is hyperthermia? [healthyone.org]

Central Fever

BACKGROUND: Central hyperthermia is an unresolved riddle; this study tries to define its characteristics. [ncbi.nlm.nih.gov]

Bromocriptine was used to treat the prolonged central hyperthermia, after which the fever did not exceed 39°C. [dovepress.com]

Patients with GH deficiency have a reduced sweating capacity which increases the risk of developing hyperthermia. [ncbi.nlm.nih.gov]

Acute Exertional Rhabdomyolysis

[…] features, including hyperthermia, muscle rigidity, tachycardia, and elevated serum creatine kinase. [pesquisa.bvsalud.org]

Conditions that lead to hyperthermia-related rhabdomyolysis include neuroleptic malignant syndrome and malignant hyperthermia. [36] A pediatric case series described an often [emedicine.medscape.com]

EHS involves (1) an elevated core body temperature (>40°C or >104°F) and (2) signs and symptoms of end-organ damage directly due to hyperthermia [29]. [emdocs.net]

Paroxysmal Rhabdomyolysis

Bernhardt D, Hoerder MH: Anesthesia induced myoglobinuria without hyperpyrexia-An abortive form of malignant hyperthermia, Malignant hyperthermia, 2nd ed. [anesthesiology.pubs.asahq.org]

Consequences of external causes ( T15-T35, T66-T98, 930-959, 990-995 ) General external causes Foreign body - Burn - Frostbite Other external causes Radiation poisoning - Hyperthermia [wikidoc.org]

Malignant hyperthermia. [physio-pedia.com]

Hypothermia due to Anesthesia

Romanovsky showed that certain TRPV1 antagonists cause hyperthermia – a severe side effect characterized by a marked rise in body temperature (fever). [techlaunch.arizona.edu]

Syndromes Malignant Hyperthermia Incidence of 1:15,000 episodes of general anesthesia. [openanesthesia.org]

Care should be taken to avoid hyperthermia which may potentially worsen any brain injury. [academic.oup.com]

Strychnine Poisoning

These spasms may lead to hyperthermia, profound lactic acidosis, and rhabdomyolysis. [ncbi.nlm.nih.gov]

She subsequently survived despite the development of convulsions, severe lactic acidosis (pH 6.86), hyperthermia (Temp 40.5 degrees C) and rhabdomyolysis. [ncbi.nlm.nih.gov]

Other clinical effects include hyperthermia resulting from sustained muscle activity, as well as hemodynamic instability. [calpoison.org]