Hypoalbuminemia: Causes & Reasons

Possible Causes for Hypoalbuminemia

Labs were remarkable for microcytic anemia and severe hypoalbuminemia. Endoscopy showed numerous polyps scattered throughout the colon. [gastrores.org]

Here we report a 63-year-old male presenting with diffuse gastrointestinal polyposis, onychodystrophy, cutaneous pigmentation, alopecia, diarrhea, hypoalbuminemia and lower [ncbi.nlm.nih.gov]

Cronkhite-Canada syndrome has a high mortality rate up to 45∼60% due to nutritional absorption disturbance, hypoalbuminemia, recurrent infection, sepsis, heart failure and [e-ce.org]

Nephrotic Syndrome

Neither study specifically addressed the management of hypoalbuminemia. [emedicine.medscape.com]

Patients present with marked edema, proteinuria, hypoalbuminemia, and often hyperlipidemia 1. [radiopaedia.org]

May be associated with hypoalbuminemia and hypercholesterolemia. [icd9data.com]

Minimal Change Nephropathy

A satisfactory response characterized by correction of hypoalbuminemia, clearance of proteinuria, and an increase of endogenous creatinine clearance occurred with corticosteroid [ncbi.nlm.nih.gov]

Nephrotic range proteinuria without severe hypoalbuminemia was detected during the 25-day course of oliguric renal failure. Renal vein thrombosis was excluded. [ncbi.nlm.nih.gov]

[…] segmental glomerulosclerosis (FSGS), and membranous nephropathy (MN) are the most common causes of the nephrotic syndrome, diagnosed by demonstrating edema, proteinuria, hypoalbuminemia [mayoclinic.pure.elsevier.com]

Capillary Leak Syndrome

The condition is characterized by recurrent episodes of severe capillary hyperpermeability resulting in severe hemoconcentration, hypoalbuminemia, hypovolemia and shock. [ncbi.nlm.nih.gov]

Adult subjects with systemic capillary leak syndrome (SCLS) present with acute and recurrent episodes of vascular leak manifesting as severe hypotension, hypoalbuminemia, [ncbi.nlm.nih.gov]

A 65-year-old Japanese woman was admitted to our hospital because of severe hypovolemic shock with metabolic acidosis and hemoconcentration and hypoalbuminemia. [ncbi.nlm.nih.gov]

Protein-Losing Enteropathy

BACKGROUND: Hypoalbuminemia commonly observed in cirrhosis is considered to be mainly related to hepatocellular dysfunction. [ncbi.nlm.nih.gov]

This clinical condition should be suspected in the presence of persistent hypoalbuminemia despite normal liver function, adequate protein intake, and no significant proteinuria [ncbi.nlm.nih.gov]

Treatment with oral prednisolone significantly improved his clinical symptoms and hypoalbuminemia. [ncbi.nlm.nih.gov]

Multicentric Castleman's Disease

In each case, tocilizumab alleviated symptoms, including generalized fatigue, pyrexia, and alleviated biochemical abnormalities, including anemia, hypoalbuminemia, hypergammaglobulinemia [ncbi.nlm.nih.gov]

Indicators of inflammation were remarkable: she had extremely high levels of serum interleukin-6 (IL-6) (398 pg/ml) in addition to hypergammaglobulinemia and hypoalbuminemia [ncbi.nlm.nih.gov]

Laboratory and clinical Minor Criteria include elevated C-reactive protein or erythrocyte sedimentation rate, anemia, thrombocytopenia or thrombocytosis, hypoalbuminemia, [ncbi.nlm.nih.gov]

Menetrier Disease

Mutant mice were found to have an increased stomach weight, enlarged gastric folds with cystic dilatation, hypergastrinemia, hypoalbuminemia, increased mucus secretion and [joi.jlc.jst.go.jp]

A cranioventral abdominal mass, anemia, hypoproteinemia, and hypoalbuminemia were the prominent abnormal findings. [ncbi.nlm.nih.gov]

It is associated with hypoalbuminemia due to albumin loss from the stomach. [icd9data.com]

Ataxia-Oculomotor Apraxia Syndrome

Acronym AOA Synonyms AOA1 Ataxia early-onset with oculomotor apraxia and hypoalbuminemia Ataxia-oculomotor apraxia 1 Cerebellar ataxia early-onset with hypoalbuminemia EAOH [uniprot.org]

Familial early onset cerebellar ataxia with hypoalbuminemia. No To Shinkei. 1995;47:289–94. [ncbi.nlm.nih.gov]

: A hereditary ataxia associated with hypoalbuminemia and hyperlipidemia: a varian form of Friedreich’s disease or a new clinical entity? [link.springer.com]

Analbuminemia

Evaluation of the patient's kindred revealed no members with hypoalbuminemia. [amjmed.com]

I should like to begin this discussion on hypoalbuminemia by showing an illustrative case (figure 1). [annals.org]

Heart Failure. ( 30799337 ) Yatsu S...Daida H 2019 6 Hypoalbuminemia and the Risk of Acute Kidney Injury in Sepsis. ( 30882443 ) Wiedermann CJ 2019 7 Hypoalbuminemia as predictor [malacards.org]

Renal Amyloidosis

The patient was put on Colchicine and anticoagulants seeing the major hypoalbuminemia. [ecco-ibd.eu]

The laboratory work-up showed nephrotic-range proteinuria and hypoalbuminemia and normal renal function despite bilateral shrunken kidneys revealed by the abdominal ultrasound [ncbi.nlm.nih.gov]

Nephrotic-range proteinuria and hypoalbuminemia were present, and a renal biopsy revealed amyloidosis. [ncbi.nlm.nih.gov]

Exfoliative Dermatitis

Also, it affects the production and metabolism of an important carrier protein called albumin leading to a condition called hypoalbuminemia, which is very devastating and [aarogya.com]

Increased dehydration due to transpiration (similar to burns) All lead to negative nitrogen balance and characterized by edema, hypoalbuminemia, loss of muscle mass. [slideshare.net]

Systemic and potentially life-threatening complications include fluid and electrolyte imbalance, thermoregulatory disturbance, fever, tachycardia, high-output failure, hypoalbuminemia [accessmedicine.mhmedical.com]

Kwashiorkor

Systemic manifestations include peripheral edema, liver disease, neurologic changes, diarrhea, weight loss, and hypoalbuminemia. [ncbi.nlm.nih.gov]

It is characterized by marked hypoalbuminemia, anemia, edema, pot belly, depigmentation of the skin, loss of hair or change in hair color to red, and bulky stools containing [medical-dictionary.thefreedictionary.com]

[…] amino acids kwa·shi·or·kor ( kwah-shē-ōr'kōr ) A disease seen in African children 1-3 years old, due to dietary deficiency, particularly of protein; characterized by marked hypoalbuminemia [medical-dictionary.thefreedictionary.com]

Liver Abscess

[…] tests Complete blood count : neutrophilic leukocytosis, normocytic normochromic anemia Liver function tests : and enzymes: ↑ alkaline phosphatase ( 90% ), ↑ AST and ALT ;, hypoalbuminemia [amboss.com]

A worse prognosis may be expected when there is a delay in diagnosis; multiple organisms cultured from blood; jaundice; hypoalbuminemia; a pleural effusion; or other associated [enotes.tripod.com]

Our results showed elevated liver enzymes and a higher frequency of hypoalbuminemia associated with pyogenic abscesses compared to other studies8. [scielo.org.co]

Secondary Amyloidosis

We report a patient with severe hypoalbuminemia in whom endoscopy revealed widespread ulceration of the small intestine. [ncbi.nlm.nih.gov]

The level of proteinuria and renal functions remained stable and the hypoalbuminemia returned to normal. [ncbi.nlm.nih.gov]

Laboratory tests showed an increase of inflammatory reactants, anemia, hypocalcemia, and severe hypoalbuminemia and hypoproteinemia. [ncbi.nlm.nih.gov]

Amebic Liver Abscess

All patients had abnormal liver scan, positive amebic serology, and hypoalbuminemia. [ncbi.nlm.nih.gov]

A stepwise logistic regression suggested that a bilirubin level >3.5 mg/dl, encephalopathy, volume of abscess cavity, hypoalbuminemia (serum albumin level [ncbi.nlm.nih.gov]

Of these, 63% had a condition consistent with severe immunosuppression, such as infection with the human immunodeficiency virus (HIV), malnourishment with severe hypoalbuminemia [ncbi.nlm.nih.gov]

Pseudomembranous Colitis

On admission, leukocytosis was found in 79% of patients, > 20,000/mm3 in half of them; 60% were anemic, 60% had elevated erythrocyte sedimentation rate, and 78% had hypoalbuminemia [ncbi.nlm.nih.gov]

Features considered nonspecific but suggestive of Clostridium difficile infection include leukocytosis, hypoalbuminemia and faecal leukocytes and occult blood. [histopathology-india.net]

(most common gastrointestinal symptom) 8. peripheral leukocyte count (10,000 to 20,000/mm3, but it may be much higher.) hypoalbuminemia – due to loss of protein in the stool [slideshare.net]

Cardiac Cirrhosis

Liver biopsy may be indicated in patients with cardiac ascites and hypoalbuminemia before transplantation [25]. [ejcts.oxfordjournals.org]

Hypoalbuminemia is rarely less than 2.5 g/dL. This factor is an independent predictor of death in patients with acute on chronic heart failure. [ncbi.nlm.nih.gov]

The liver function tests were abnormal with mildly elevated liver enzymes, bilirubin of 3.4 mg/dl and hypoalbuminemia. [omicsonline.org]

Intestinal Disease

[…] cases with small-intestinal hemorrhage, 39 with abdominal pain, 7 with diarrhea, 13 with abdominal distention, 3 cases with malnutrition, and 1 with diarrhea and refractory hypoalbuminemia [ncbi.nlm.nih.gov]

Outpatient follow-up revealed hypoalbuminemia in May 2003 and upper gastrointestinal endoscopy showed duodenal mucosal nodularity. [ncbi.nlm.nih.gov]

Protein-losing enteropathy and hypoalbuminemia in AIDS. AIDS. 1993 Jun. 7(6):837-40. [Medline]. Waldmann TA, Wochner RD, Strober W. [emedicine.com]

Adult-Onset Still Disease

AOSD patients with RHS showed higher frequencies of leukopenia, anemia, thrombocytopenia, hypoalbuminemia, hypofibrinogenemia, hypertriglyceridemia, hyperferritinemia, and [ncbi.nlm.nih.gov]

Laboratory tests support the inflammatory nature of the disorder with leukocytosis, anemia of chronic disease, hypoalbuminemia, and hyperferritinemia. [rheumnow.com]

Thus, hypoalbuminemia, elevated hepatic enzymes (primarily transaminases), and aldolase elevations are seen in 60-75% of patients during active inflammatory phase of the disease [rheumaknowledgy.com]

Alcoholic Hepatitis

A blood test showed leukophilia, mild hypoalbuminemia, hyperbilirubinemia, hepatobiliary injury and coagulopathy. [ncbi.nlm.nih.gov]

Hypoalbuminemia is a medical condition where levels of albumin in blood serum are abnormally low. It is a specific form of hypoproteinemia. [quitalcohol.com]

– Mild elevation in alkaline phosphatase Albumin (frequent hypoalbuminemia) Prothrombin time/international normalized ratio (INR) (frequent coagulopathy) Complete blood [clinicaladvisor.com]

Tropical Sprue

A significant relationship was not observed between PT and hypoalbuminemia. Patients with more severe damage by intestinal biopsy tended to have lower PT values. [ncbi.nlm.nih.gov]

Protein-losing enteropathy and hypoalbuminemia in AIDS. AIDS. 1993 Jun. 7(6):837-40. [Medline]. Waldmann TA, Wochner RD, Strober W. [emedicine.medscape.com]

Protein-losing enteropathy is characterized by more loss of proteins via the gastrointestinal tract than synthesis leading to hypoalbuminemia. [emedicine.medscape.com]

Ileocecal Tuberculosis

Her problems persisted and she developed malnutrition, hypoalbuminemia, and intermittent fever and was started on treatment for tuberculosis. [journals.lww.com]

Hematologic findings are nonspecific and include raised erythrocyte sedimentation rate, anemia and hypoalbuminemia. [ncbi.nlm.nih.gov]

He had anemia, hypoalbuminemia and abdominal pain, aggravated on eating wheat. Duodenal histology suggested celiac disease with improvement on dietary gluten exclusion. [journals.lww.com]

Portal Cirrhosis

Nail changes: – Muehrcke's nails: Paired horizontal bands separated by normal color due to hypoalbuminemia,[8] from inadequate production of albumin, which is solely made [slideshare.net]

Leukonychia/Terry’s nails Horizontal white bands or proximal white nail plate Hypoalbuminemia Decrease in vascularity and an increase in connective tissue in the nail bed [pathophys.org]

Spironolactone and furosemide to manage ascites and edema in patients with hypoalbuminemia In cases of coagulation factor deficiency (possibly combined with thrombocytopenia [amboss.com]

Miliary Tuberculosis of the Liver

The laboratory investigations frequently show an increase in alkaline phosphatase, with normal to mildly increased transaminases, anemia, hypoalbuminemia, hypergammaglobulinaemia [academic.oup.com]

As in first case, abnormalities in the liver function tests reported 2,8,9 include raised levels of alkaline phosphatase and Gamma-GT and hypoalbuminemia. [jpma.org.pk]

Marasmus

Vital signs: bradycardia, hypothermia CBC: to evaluate for anemia, leukocytosis CMP: to monitor for hypoglycemia and hypoalbuminemia Prealbumin: sensitive index of protein [cancertherapyadvisor.com]

Unlike marasmus, marked protein deprivation is associated with severe loss of the visceral protein compartment, and the resultant hypoalbuminemia gives rise to generalized [humpath.com]

Amyloidosis

In the present case, intestinal protein loss might explain the presence of hypoalbuminemia and diarrhea. [scielo.isciii.es]

The patient had anemia and hypoalbuminemia. [semanticscholar.org]

On further evaluation, he had hypoalbuminemia, significant nephrotic-range proteinuria, and elevated levels of anti-tissue transglutaminase. [ncbi.nlm.nih.gov]

Chronic Glomerulonephritis

[…] to the stage (I - IV) • - NS – clinical and laboratory syndrome wich includes: • Proteinuriua more than 1 g / m 2 24 hours (3 ,5 -4 g / 24 hours ), • Hypoproteinemia with hypoalbuminemia [intranet.tdmu.edu.ua]

Profound proteinuria (>3.5 g/day) resulting in hypoalbuminemia and consequent edema are prominent symptoms, whereas hypertension and vascular abnormalities are absent in the [symptoma.com]

[…] glomerulonephritis urinalysis: proteinuria, hematuria, cell debris (red cells and casts), increased urine specific gravity Electrolytes In glomerulonephritis hyperkalemia, hypoalbuminemia [quizlet.com]

Adult-Onset Citrullinemia Type 2

General physical examination and all routine investigations including cerebrospinal fluid examination were normal except for hypoalbuminemia (2.9 g/dl) and mild transaminitis [academic.oup.com]

] 0000738 Hepatomegaly Enlarged liver 0002240 Hypertriglyceridemia Increased plasma triglycerides Increased serum triglycerides Increased triglycerides [ more ] 0002155 Hypoalbuminemia [rarediseases.info.nih.gov]

Rocky Mountain Spotted Fever

The endothelial cell injury triggers a series of important physiological modifications, like increased vascular permeability, edema, hypotension and hypoalbuminemia, which [symptoma.com]

Serum biochemical abnormalities may include hypoproteinemia, hypoalbuminemia, azotemia, hyponatremia, hypocalcemia, and increased liver enzyme activities. [msdvetmanual.com]

The major pathophysiologic effect of endothelial cell injury is increased vascular permeability, which results in edema, hypovolemia, hypotension, and hypoalbuminemia. [emedicine.com]

Macronodular Cirrhosis

Serum albumin: significant liver disease results in hypoalbuminemia. 10. [encyclopedia.lubopitko-bg.com]

Muehrcke's lines – paired horizontal bands separated by normal color resulting from hypoalbuminemia (inadequate production of albumin). [en.wikipedia.org]

[…] gastritis, bleeding esophageal varices, PUD, bleeding hemorrhoids) GENITALIA: Testicular atrophy in males (chronic liver disease, hemochromatosis) EXTREMITIES: Pedal edema (hypoalbuminemia [encyclopedia.lubopitko-bg.com]