Jaundice: Causes & Reasons

Possible Causes for Jaundice

After "simple" cholecystectomy for lithiasis, biliary disorders can appear, with the onset more than 3 years postoperative, like cholangitis or transitory jaundice. [ncbi.nlm.nih.gov]

You notice jaundice; gallstones may be obstructing the bile duct, causing bile to back up into the liver and seep into your bloodstream. [webmd.com]

But if it gets down to common bile duct than it can also cause obstructive jaundice. Right upper quadrant pain. [youtube.com]

Cholestatic Jaundice

Familial acholuric jaundice is another name for the hereditary form of hemolytic jaundice. breast milk jaundice elevated unconjugated bilirubin in some breast-fed infants [medical-dictionary.thefreedictionary.com]

Our report highlights the varied aetiology of obstructive jaundice and the importance of including biliary ascariasis in the differential diagnosis of the jaundiced patient [ncbi.nlm.nih.gov]

Obstructive jaundice secondary to abdominal tuberculosis is extremely rare. [ncbi.nlm.nih.gov]

Infectious Mononucleosis

We report a case of infectious mononucleosis in a 72-year old jaundiced gentleman with ferritin level of 2438 that normalised on clinical improvement. [ncbi.nlm.nih.gov]

[…] patient between 16 and 25 years old who complains of sore throat and fever is more likely to have infectious mononucleosis than another disease; and if - in addition - he is jaundiced [ncbi.nlm.nih.gov]

[…] mononucleosis due to Epstein-Barr virus (EBV) infection sometimes causes acute hepatitis, which is usually self-limiting with mildly elevated transaminases, but rarely with jaundice [ncbi.nlm.nih.gov]

Hemolytic Anemia

The existence of a primary form of acquired hemolytic jaundice has been questioned more and FULL TEXT [annals.org]

The diagnosis of Zieve syndrome was confirmed based on hemolysis and cholestatic jaundice secondary to alcoholic liver disease and heavy drinking. [ncbi.nlm.nih.gov]

Jaundice (yellowing of the skin or eyes) occurs because of the increase in bilirubin. Jaundice may appear or increase at times of illness. [stjude.org]

Liver Cirrhosis

Differential diagnosis from obstructive jaundice and a severe prognosis without alcohol abstinence make early diagnosis mandatory. [ncbi.nlm.nih.gov]

Jaundice may complicate any stage of cirrhosis. [britannica.com]

The patient also presented with acute encephalopathy, jaundice, right upper quadrant abdominal pain and hyperbilirubinaemia (total bilirubin of 8.1 mg/dL with direct bilirubin [ncbi.nlm.nih.gov]

Choledocholithiasis

[…] colic Charcot’s triad Ascending cholangitis  Suppurative cholangitis Reynold’s pentad Persistent pain, fever, jaundice, shock & AMS  Painful jaundice with dark color [slideshare.net]

You develop jaundice. You have other symptoms of choledocholithiasis. Gallstone in the bile duct; Bile duct stone Fogel EL, Sherman S. [nlm.nih.gov]

Cholangitis, Obstructive Jaundice) How is Common Bile Duct Stone (Choledocholithiasis, Cholangitis, Obstructive Jaundice) Diagnosed? [healthengine.com.au]

Hepatitis

[citation needed] Diagnostic tests[24] Function test Pre-hepatic jaundice Jaundice due to the liver Post-hepatic jaundice Total bilirubin Normal / increased Increased Conjugated [en.wikipedia.org]

Common symptoms include jaundice, nausea, chills, rigors, diaphoresis, fatigue, and abdominal pain. [ncbi.nlm.nih.gov]

Hepatic Disorders, Jaundice, and Hepatic Failure Sections: Hepatic Disorders, Jaundice, and Hepatic Failure: Introduction, Epidemiology, Pathophysiology, Clinical Features [web.archive.org]

Portal Cirrhosis

It has a lengthy latent period, usually followed by the sudden appearance of abdominal pain and swelling, hematemesis, dependent edema, or jaundice. [medical-dictionary.thefreedictionary.com]

Yellow color in the skin, mucous membranes, or eyes (jaundice). [marylandhearingcenter.com]

[…] within the normal range in patients with latent, asymptomatic cirrhosis, 13, 14 whereas it was consistently reduced in patients with portal cirrhosis accompanied by severe jaundice [annals.org]

Alcoholic Liver Disease

The term acute alcoholic cholestasis is suggested for this apparently distinct syndrome of cholestatic jaundice in the absence of hepatitis. [ncbi.nlm.nih.gov]

The diagnosis of Zieve syndrome was confirmed based on hemolysis and cholestatic jaundice secondary to alcoholic liver disease and heavy drinking. [ncbi.nlm.nih.gov]

There is described the case of a 27-year-old patient with jaundice and hepatic encephalopathy with long history of alcohol dependence and substance abuse. [ncbi.nlm.nih.gov]

Biliary Carcinoma

We present a woman diagnosed with metastatic breast cancer in the CBD after presenting with obstructive jaundice. [karger.com]

We present the third case of metastatic lung cancer to the common bile duct presenting as abdominal distention and jaundice. [omicsonline.org]

Jaundice is a common symptom of bile duct cancer. Jaundice causes the skin and the whites of the eyes to turn yellow. [cancer.net]

Bile Duct Stricture

Laboratory reports suggested obstructive jaundice. [ncbi.nlm.nih.gov]

Biloma and jaundice are serious complications associated with bile duct strictures. [ncbi.nlm.nih.gov]

Obstructive jaundice, first evident at 3 weeks of age, became progressively severe. [ncbi.nlm.nih.gov]

Cholestasis

The outcomes of patients with cholestatic jaundice depend on the cause. [ncbi.nlm.nih.gov]

Our patient, a 76 year old female, with no past medical history, presented with progressive weakness followed by the onset of jaundice. [omicsonline.org]

A 35 year-old-woman with vitiligo, jaundice and cholestasis fulfilled serological, biochemical and histological criteria for PBC/AIH overlap. [ncbi.nlm.nih.gov]

Macronodular Cirrhosis

List 3 causes of pre-hepatic jaundice List 2 causes of post-hepatic jaundice. List 3 causes of hepatic jaundice. [quizlet.com]

Pruritus is reported when significant jaundice is present. [medical-dictionary.thefreedictionary.com]

jaundice, Macro, autopsy (70350) Eyes, jaundice, Macro, autopsy (70351) Kidney, cholemic nefrosis: Kidney, cholemic nefrosis, Macro, autopsy (70360) Kidney, cholemic nefrosis [atlases.muni.cz]

Cryptogenic Cirrhosis

Age, jaundice, spiders, palmar erythema and factor V showed a statistically significant difference of the cryptogenic cirrhosis when compared with both alcoholic and viral [ncbi.nlm.nih.gov]

Symptoms of cryptogenic cirrhosis are no different than the symptoms in any other type of cirrhosis: jaundice, abdominal swelling, weight loss, fever and blood in the stool [symptoma.com]

Kidney failure Jaundice Severe itching Gallstones A small number of people with cirrhosis get liver cancer. [icdlist.com]

Hereditary Spherocytosis

This case also highlights the fact that physicians should consider concomitant hemolytic disease in patients in whom jaundice and infections that rarely cause jaundice coexist [ncbi.nlm.nih.gov]

In this article the authors present a case of pathological neonatal jaundice resistant to phototherapy in a baby with a family history of Gilbert's syndrome and hereditary [ncbi.nlm.nih.gov]

[…] of hereditary spherocytosis (HS) in a newborn infant is generally made on the basis of a positive family history, spherocytes on blood film and Coombs-negative hemolytic jaundice [ncbi.nlm.nih.gov]

Cholecystitis

The outcomes of patients with cholestatic jaundice depend on the cause. [ncbi.nlm.nih.gov]

A 61-year-old man presented with upper abdominal pain and jaundice. [ncbi.nlm.nih.gov]

[…] patient had right upper quadrant pain with sclera was transferred from emergency room to the hospital, she was proposed to have acute cholecystitis, gallstones, obstructive jaundice [ncbi.nlm.nih.gov]

Pancreatitis

Detection and diagnosis When making a diagnosis, the doctor checks for signs of jaundice, weakness, emaciation, diarrhea and/or foul-smelling stool. [gwhospital.com]

Detection and Diagnosis When making a diagnosis, the doctor checks for signs of jaundice, weakness, emaciation, diarrhea and/or foul-smelling stool. [aikenregional.com]

Symptoms may be attributable to the failure of: biliary outflow: jaundice exocrine function: malabsorption endocrine function: diabetes Acute pancreatitis and chronic pancreatitis [radiopaedia.org]

Acute Cholecystitis

The outcomes of patients with cholestatic jaundice depend on the cause. [ncbi.nlm.nih.gov]

Courvoisier’s Law: The presence of jaundice, palpable gallbladder means that the jaundice is unlikely to be due to stones. [armandoh.org]

A 61-year-old man presented with upper abdominal pain and jaundice. [ncbi.nlm.nih.gov]

Neonatal Jaundice

Breast milk jaundice is common. [kidshealthwa.com]

Treatment of neonatal jaundice was the focus of the second study. [acutecaretesting.org]

Pathologic Jaundice When a baby is born with jaundice, it’s always bad. This is pathologic jaundice, and it’s almost always caught before the baby goes home. [pemplaybook.org]

Ascending Cholangitis

The outcomes of patients with cholestatic jaundice depend on the cause. [ncbi.nlm.nih.gov]

Key Clinical Questions What causes jaundice? How are biliary obstruction and cholangitis diagnosed? What are the best imaging modalities? [accessmedicine.mhmedical.com]

Jaundice results from a pathologic process that interferes with the normal metabolism and excretion of bilirubin ( Figure 158-1 ). [accessmedicine.mhmedical.com]

Primary Sclerosing Cholangitis

As the disease progresses, individuals may develop jaundice (yellowing of skin and darkening of urine). Jaundice is due to the accumulation of bilirubin in the body. [emedicinehealth.com]

[…] the space between the lining of the abdomen and abdominal organs) and varices (enlarged veins) Biliary cirrhosis (inflammation of the bile ducts) Liver failure Persistent jaundice [medlineplus.gov]

UDCA is now considered if there is worsening pruritus or jaundice. [emedicinehealth.com]

Secondary Sclerosing Cholangitis

Overall 70% of patients with sclerosing cholangitis had jaundice vs. 25% without sclerosing cholangitis (p CONCLUSIONS: Our results indicate that drugs can lead to bile duct [ncbi.nlm.nih.gov]

Cholestatic jaundice as a paraneoplastic feature of secondary sclerosing cholangitis is rare in Hodgkin’s lymphoma. [jamc.ayubmed.edu.pk]

A 50 year male presented with acute onset jaundice, significant weight loss and elevated liver enzymes with clinico-radiological suspicion of cholangiocarcinoma. [ncbi.nlm.nih.gov]

Viral Hepatitis

Jaundice is a rare clinical presentation in typhoid fever, therefore hepatitis A should be considered in typhoid fever and jaundice because both enterically transmitted disease [ncbi.nlm.nih.gov]

The dilemma in which an anesthesiologist is put is whether to promise the anesthesia straightaway in the face of a demonstrable acute jaundice in pregnancy to advise a postponement [ncbi.nlm.nih.gov]

Liver Failure

Rare disease associated with jaundice, coagulopathy, and hepatic encephalopathy. [bestpractice.bmj.com]

One of the first signs of a problem with your child’s liver is jaundice. Jaundice happens when the liver is unable to remove bilirubin, a yellow pigment, from the blood. [seattlechildrens.org]

The insult should be a hepatic one and presentation in the form of liver failure (jaundice, encephalopathy, coagulopathy, ascites) with or without extrahepatic organ failure [ncbi.nlm.nih.gov]

Pancreatic Adenocarcinoma

Malignant biliary obstruction occurs as a result of tumor compression of the common bile duct, leading to severe jaundice. [pancreapedia.org]

This patient initially presented with painless jaundice and computed tomography (CT) revealed a mass in the head of the pancreas. [ncbi.nlm.nih.gov]

CASE REPORT: A 38-year-old man with a synchronous 6-month history of thyroid swelling, presented with epigastric pain and signs of obstructive jaundice. [ncbi.nlm.nih.gov]

Hepatocellular Carcinoma

Jaundice is not necessarily a contraindication for surgery. [ncbi.nlm.nih.gov]

Symptoms include abdominal pain or tenderness, jaundice, enlarged abdomen, and easy bruising or bleeding. [medicinenet.com]

She was subsequently diagnosed with HCC and became severely jaundiced, hypotensive and tachycardic with metabolic acidosis. [journals.co.za]

Malignant Neoplasm of the Pancreas

Jaundice and related symptoms Jaundice is yellowing of the eyes and skin. [cancer.org]

In patients with inoperable lesions and jaundice, endoscopic placement of a bile duct stent relieves jaundice. Duodenal stenting is frequently done. [msdmanuals.com]

This can also cause jaundice. [cancer.org]

Drug-Induced Toxic Hepatitis

Combination of estrogenic and progestational steroids; estrogen is primarily responsible Intrahepatic cholestasis Pruritus and jaundice Susceptible patients: idiopathic jaundice [slideshare.net]

Anorexia, nausea, and vomiting are the usual symptoms; jaundice and hepatomegaly are noted on physical assessment. [hepatitiscentral.com]

Neoplastic obstruction of the bile ducts can also cause jaundice, although pain is frequently absent. [nature.com]

Toxic Liver Disease

In addition to the elevation of ALT and AST levels, cases of liver necrosis, jaundice, and fulminant hepatitis with and without jaundice have occurred. [emedicine.medscape.com]

Others may have Loss of appetite Nausea and vomiting Diarrhea Dark-colored urine and pale bowel movements Stomach pain Jaundice, yellowing of skin and eyes Some forms of hepatitis [icdlist.com]

Jaundice may then follow. Most patients with isoniazid hepatitis recover fully and promptly after stopping the drug. [medicinenet.com]

Isoniazid Hepatitis

However, jaundice was notably absent in the patients with enzyme elevations and prompted a further investigation into the possible effect of INH on bilirubin metabolism. [ncbi.nlm.nih.gov]

Isoniazid jaundice and its relationship to iproniazid jaundice. Tubercle 1962; 43: 375-81. [livertox.nih.gov]

A prodromal period characterized by fatigue, weakness, anorexia, and malaise was noted in all patients before the appearance of jaundice. [annals.org]