Muscle Weakness: Causes & Reasons

Possible Causes for Muscle Weakness

Apart from the well-known effects on bone metabolism, this condition is also associated with muscle weakness, predominantly of the proximal muscle groups. [ncbi.nlm.nih.gov]

All had generalized bone pain and tenderness, muscle weakness, stooping posture, difficulty walking, and waddling gait due to severe proximal muscle weakness for a period [ncbi.nlm.nih.gov]

We report a four-year-old African boy referred for proximal muscle weakness, fatigability and episodic limb pain. [ncbi.nlm.nih.gov]

Hyperkalemia

Muscle weakness Other names Myasthenia Specialty Neurology Muscle weakness is a lack of muscle strength. [en.wikipedia.org]

Careful monitoring of electrocardiogram changes and muscle weakness in hyperkalemia is important to determine its functional consequences. [resources.acls.com]

Signs and symptoms include muscle weakness, paralysis, hypothermia, and cardiac abnormalities (irregular conduction and arrhythmias). [visualdx.com]

Hyperthyroidism

Muscle weakness was more severe in the proximal site than in the distal site. [ncbi.nlm.nih.gov]

She presented with muscle weakness, nausea, vomiting, and diarrhea since one week. The initial diagnosis was TPP. [ncbi.nlm.nih.gov]

These include: Increased heart rate Hand tremor Brisk response to tapping with a reflex hammer Excessive sweating Muscle weakness Protruding eyes If your doctor suspects hyperthyroidism [drugs.com]

Cushing Syndrome

The clinical sign indicative for CS leading to referral to the endocrinologist was muscle weakness in the man and plethora in the woman. [ncbi.nlm.nih.gov]

Symptoms include a round face, thin arms and legs, severe fatigue and muscle weakness, high blood pressure and high blood sugar, purple or pink stretch marks on the skin, [icd10data.com]

Cushing syndrome is characterized by truncal obesity, growth deceleration, skin changes, muscle weakness, and hypertension. [ncbi.nlm.nih.gov]

Muscular Dystrophy

It causes progressive weakness in muscles of the face, arms, legs, and around the shoulders and chest. [ninds.nih.gov]

Weakness of the back muscles can cause scoliosis, while weakness of the abdominal muscles can be the cause of a sagging belly. [nlm.nih.gov]

[…] disorders characterized by muscle weakness and eventual death of the muscle tissues. [icd9data.com]

Duchenne Muscular Dystrophy

Muscle weakness Other names Myasthenia Specialty Neurology Muscle weakness is a lack of muscle strength. [en.wikipedia.org]

Occasionally, however, females who carry a DMD gene mutation may have muscle weakness and cramping. [ghr.nlm.nih.gov]

Proximal muscle weakness affects muscles closest to the body's midline, while distal muscle weakness affects muscles further out on the limbs. [en.wikipedia.org]

Graves Disease

On neurological examination the patient was presented with muscle weakness, muscle atrophy (in face and sternocleidomastoid muscles), features of myotonia and apocamnosis [ncbi.nlm.nih.gov]

weakness and myopathy • Increased DTR • Increased motor activity • Fatigue Cardiovascular • Tachycardia • Palpitations • Repiratory muscle weakness • Increased RR and HR [physio-pedia.com]

Symptoms of hyperthyroidis m include rapid heartbeat, muscle weakness, disturbed sleep, and irritability. [quidel.com]

Rhabdomyolysis

A 71-year-old man was hospitalized because of muscle weakness of the lower limbs that persisted for 1 month. [ncbi.nlm.nih.gov]

Examination revealed proximal symmetrical muscle weakness and arthralgia. The immunological study, electromyography and muscle biopsy confirmed polymyositis. [ncbi.nlm.nih.gov]

Abstract A 91-year-old male was admitted to the hospital for worsening muscle weakness, muscle pain, and unexplained soreness for the past 10 days. [ncbi.nlm.nih.gov]

Motor Neuron Disease

[…] wasting and weakness, absent reflexes, loss of weight and muscle twitching. [mndnsw.asn.au]

Onset was in the second to fourth decade with finger extension weakness, progressing to other distal and sometimes more proximal muscles. [ncbi.nlm.nih.gov]

He developed gait disturbance and weakness of lower limbs at age 52 years. Because of progressive muscle weakness and atrophy, he became bed-ridden at age 65. [ncbi.nlm.nih.gov]

Multifocal Motor Neuropathy

Her disease was difficult to manage with various immunosuppressants, and the muscle weakness eventually progressed to involve the respiratory muscles, necessitating mechanical [ncbi.nlm.nih.gov]

The main symptom is progressive muscle weakness of the arms and legs. [rarediseases.org]

Muscle imbalance and weakness can become so severe that the involved extremity can be rendered nonfunctional. [ncbi.nlm.nih.gov]

Hyponatremia

A 52-year-old Sri Lankan man presented with anorexia, nausea, fatigue, generalized muscle weakness, and cramps for 1 week. [ncbi.nlm.nih.gov]

Headache, confusion, or fatigue Low blood pressure Loss of energy Muscle weakness, twitching, or cramps Seizures or coma Restlessness or bad temper How do you treat hyponatremia [kidney.org]

Muscle weakness. Poor appetite that does not improve. Shortness of breath, chest pain or discomfort; should be evaluated immediately. [chemocare.com]

Addison Disease

The physical examination was completely normal except for muscle weakness, hyperpigmentation on labial mucosa and skin in a patient. [ncbi.nlm.nih.gov]

A medical condition in which the adrenal glands do not produce enough cortisol or, in some cases, aldosterone, causing such problems as weight loss, muscle weakness, fatigue [diabetesselfmanagement.com]

Symptoms & Causes The most common symptoms are fatigue, muscle weakness, loss of appetite, weight loss, and abdominal pain. [niddk.nih.gov]

Hypokalemia

Muscle weakness and spasms. Tingling and numbness. More severe cases of low potassium may cause signs and symptoms such as: Muscle twitches. Muscle cramps. [my.clevelandclinic.org]

The effects of low potassium include may cause heart palpitations, muscle cramps, muscle aches, and muscle weakness. [medicinenet.com]

Eleven patients had a history of recurring muscle weakness. All patients had quadraparesis (muscle weakness in all four limbs); in 10 patients the weakness was severe. [acutecaretesting.org]

Porphyria

Some types of acute porphyrias cause muscle weakness. Muscle problems can be life-threatening if weakness affects the muscles that make respiration (breathing) possible. [my.clevelandclinic.org]

Besides having abdominal and nerve pain, the patient may suffer rapid heartbeat, mania, muscle cramps, muscle weakness, breathing problems, hallucinations, and coma. [rxlist.com]

Acute porphyria can also affect the nervous system causing numbness and muscle weakness. [recordatirarediseases.com]

Acute Hepatic Porphyria

It’s also important to address the other symptoms of AIP, like a racing heart (tachycardia) and muscle weakness, because they can lead to complications. [verywellhealth.com]

Muscle weakness. Nausea and vomiting. Constipation. Hypertensive crises. Increased heart rate. Do you have any of these symptoms? [cun.es]

Consider AIP if typical clinical features are seen in the absence of other causes (e.g., unexplained severe abdominal pain accompanied by muscle weakness and dark urine). [amboss.com]

Guillain-Barré Syndrome

But weakness that increases over several days is also common. Muscle weakness or loss of muscle function (paralysis) affects both sides of the body. [nlm.nih.gov]

This leads to nerve inflammation that causes muscle weakness or paralysis and other symptoms. The exact cause of GBS is unknown. [medlineplus.gov]

A medical exam may show muscle weakness. There may also be problems with blood pressure and heart rate. [nlm.nih.gov]

Acute Exertional Rhabdomyolysis

A 62-year-old man was brought to the hospital with back pain and muscle weakness accompanied by myalgia. [blog.goo.ne.jp]

Two patients who demonstrated increased muscle mass, muscle stiffness with variable degrees of muscle weakness and low levels of serum thyroxine (Hoffmann's syndrome) are [scinapse.io]

[…] of SK muscle weakness begins in face muscles (bilat or unil) diplopia, ptosis, difficult chewing, dysphagia, nasal timbre in voice limb and torso weakness may develop resp [quizlet.com]

Secondary Myopathy

Muscle weakness is a common complaint among patients presenting to family physicians. [aafp.org]

In infants, myopathy is evident from muscle weakness and hypotonia. 2 Adults may present with predominant proximal muscle weakness with difficulty in getting up from squatting [chanrejournals.com]

Muscle weakness is usually most severe in muscles of the face, neck and proximal muscles. [rarediseases.org]

Leigh's Disease

Patient often have hypotonia (weak muscle tone), dystonia (involuntary muscle contractions) and ataxia (trouble with balance). [eyewiki.aao.org]

Affected individuals may develop muscle weakness affecting the arms and legs, especially affecting the muscles of the upper arms and upper legs (proximal muscle weakness). [rarediseases.org]

NARP is characterized by proximal neurogenic muscle weakness with sensory neuropathy, ataxia, and pigmentary retinopathy. [ncbi.nlm.nih.gov]

Hypercalcemia

She had nausea, vomiting, leg pain, polyuria, polydipsia, and muscle weakness. At the time of relapse, the ionized calcium level was 1.99 mmol/L. [ncbi.nlm.nih.gov]

weakness, depression, anorexia, nausea, and constipation High level of calcium in the blood Higher than normal levels of calcium in the blood. [icd9data.com]

weakness, and weight loss. [ncbi.nlm.nih.gov]

MELAS Syndrome

Most people with MELAS have a build up of lactic acid in the blood above the normal upper limit, which can lead to vomiting, muscle weakness, abdominal pain, fatigue, and [khondrion.com]

Early symptoms may include muscle weakness and pain, recurrent headaches, loss of appetite, vomiting, and seizures. [medlineplus.gov]

This can result in temporary muscle weakness on one side of the body (hemiparesis), altered consciousness, vision and hearing loss, loss of motor skills and intellectual disability [khondrion.com]

Polymyositis

Some cases of polymyositis have manifestations of muscle weakness in the orbital muscles. Rare cases also have weaknesses in facial and bulbar muscles. [symptoma.com]

Abstract Polymyositis is an idiopathic inflammatory myopathy of unknown aetiology that affect skeletal muscles causing symmetrical, proximal muscle weakness, and also other [ncbi.nlm.nih.gov]

Polymyositis-like syndrome in hypothyroidism is a rare condition characterised by proximal muscle weakness and elevated muscle enzymes. [ncbi.nlm.nih.gov]

Limb-Girdle Muscular Dystrophy

Muscle weakness may spread from the proximal muscles to affect distal muscles. [rarediseases.org]

However, most patients in the current family showed distal as well as proximal limb weakness rather than weakness of toe and finger flexor muscles that were typical features [ncbi.nlm.nih.gov]

In addition to proximal muscle weakness, there may or may not be: Distal muscle weakness. Muscle hypertrophy. Contractures. [patient.info]

Facioscapulohumeral Muscular Dystrophy

BACKGROUND: Although muscle weakness is a hallmark of facioscapulohumeral muscular dystrophy (FSHD), the molecular mechanisms that lead to weakness in FSHD remain largely [ncbi.nlm.nih.gov]

Weakness of the back muscles can cause scoliosis, while weakness of the abdominal muscles can be the cause of a sagging belly. [nlm.nih.gov]

Patients present with muscle weakness in these anatomic areas. The muscle weakness eventually spreads to other skeletal muscles as well. [wikidata.org]

Erb Muscular Dystrophy

Muscle weakness may spread from the proximal muscles to affect distal muscles. [rarediseases.org]

It causes progressive weakness in muscles of the face, arms, legs, and around the shoulders and chest. [ninds.nih.gov]

muscle biopsy (examination of a sample of the weak muscle tissue under a microscope), and genetic testing. [msdmanuals.com]

Chronic Inflammatory Demyelinating Polyneuropathy

[…] of the muscle weakness. [ncbi.nlm.nih.gov]

The article presents a boy with progressive generalized muscle weakness and areflexia since the age of two, developed after viral infection. [ncbi.nlm.nih.gov]

Although the patient noticed little muscle weakness, an electrophysiological study demonstrated slow conduction velocities and prolonged distal latencies, with definite conduction [ncbi.nlm.nih.gov]

Congenital Muscular Dystrophy

KEYWORDS: Collagen; Fibrosis; IGF-1; Mesenchymal; Mouse; Muscular dystrophy; Skeletal muscles; Weakness [ncbi.nlm.nih.gov]

Congenital muscular dystrophy related to lamin A/C is rare and characterized by early-onset hypotonia with axial muscle weakness typically presenting with a loss in motor [ncbi.nlm.nih.gov]

Congenital muscular dystrophy (CMD) comprises a heterogeneous group of disorders with muscle weakness, hypotonia and contractures present at birth. [ncbi.nlm.nih.gov]

Dermatomyositis

The muscle weakness may come on suddenly or develop slowly over weeks or months. [medlineplus.gov]

Rash and Muscle Weakness DM is usually the easiest type of myositis to diagnose because of the skin rash, which often appears before any muscle weakness is felt. [myositis.org]

[…] out of bed due to muscle weakness Sometimes the muscle weakness also spreads to the heart, GI tract, and lungs. [hopkinsmedicine.org]

Hypokalemic Nephropathy

Careful monitoring of electrocardiogram changes and muscle weakness in hyperkalemia is important to determine its functional consequences. [acls.com]

Due to muscle weakness and cramping, exercise is not effective during the state of hypokalemia. [physio-pedia.com]

There is generalized muscle weakness, characterized by ventroflexion of the neck; other signs include weight loss, chronic vomiting and constipation. [medical-dictionary.thefreedictionary.com]

Brachial Plexus Neuritis

Brachial plexus neuritis is thought to be an immune mediated inflammatory reaction resulting in acute onset of shoulder pain followed by muscle weakness and wasting. [ncbi.nlm.nih.gov]

Within a few hours or days of the condition’s onset, affected individuals may experience muscle weakness, wasting (atrophy), numbness (hyperesthesia), and paralysis of the [diseasesatoz.com]

Pain and muscle weakness occur simultaneously. [aafp.org]