Proteinuria: Causes & Reasons

Possible Causes for Proteinuria

CONCLUSIONS: The severity of preeclampsia cannot be determined by the level of proteinuria. [ncbi.nlm.nih.gov]

[…] to the onset and severity of proteinuria. [doi.org]

Proteinuria Pronunciation Specialty Nephrology Proteinuria is the presence of excess proteins in the urine. [en.wikipedia.org]

Glomerulonephritis

Nephrotic syndrome: heavy proteinuria, hypoalbuminaemia and fluid retention. [patient.info]

IgA glomerulonephritis IgA nephropathy; a chronic form marked by a hematuria and proteinuria and by deposits of immunoglobulin A in the mesangial areas of the renal glomeruli [medical-dictionary.thefreedictionary.com]

It may present with proteinuria or nephritic syndrome, hypertension. Haematuria is rare. [patient.info]

Chronic Pyelonephritis

Abstract Massive proteinuria associated with chronic pyelonephritis is reported in five patients. [ncbi.nlm.nih.gov]

When there is massive proteinuria an associated glomerulopathy is usually present. [ncbi.nlm.nih.gov]

Proteinuria is usually minimal and when present is associated with hypertension. [ncbi.nlm.nih.gov]

Fabry Disease

It showed that the proteinuria emerged like surges, followed by temporary plasma GL-3 elevations in the early stages of classic Fabry disease. [ncbi.nlm.nih.gov]

He suffered a relapse in proteinuria which responded to increased doses of the administered recombinant enzyme. [ncbi.nlm.nih.gov]

[…] with proteinuria. [ndt.oxfordjournals.org]

Non-Allergic Interstitial Nephritis

Modest proteinuria and hyperkalemic renal tubular acidosis are common. [emedicine.medscape.com]

Injury Cryoglobuinemia Crystalglobulin-Induced Nephropathy Crystal-Induced Acute Kidney injury Cystic Kidney Disease, Acquired Cystinuria Dasatinib-Induced Nephrotic-Range Proteinuria [thekaiganfoundation.com]

modest proteinuria, kreatinin and BUN elevation, hypertension 27 Laboratory BUN, kreatinin- renal failure Low bicarbonate < 24 mEq L- acidosisph 1-2 gr/24h Protein ELFO- [slideplayer.com]

Henoch-Schönlein Purpura

KDIGO blood pressure guidelines for IgA nephropathy are advised as < 130/80 mm Hg in patients with proteinuria < 1 g/d and < 125/75 mm HG when initial proteinuria is > 1 g [clinicaladvisor.com]

Pediatricians will check children's urine for hematuria and proteinuria until these results are normal and stable. [jamanetwork.com]

[…] time and 22 patients on the proteinuria pathway. [journals.plos.org]

Minimal Change Nephropathy

proteinuria. [books.google.com]

Abstract In order to predict the steroid response in lipoid nephrosis (LN), we studied age, sex, proteinuria level, histological features and proteinuria selectivity index [ncbi.nlm.nih.gov]

The disorder is usually seen in children, when proteinuria, and less commonly hypertension and edema, present as main clinical features. [symptoma.com]

Nephrotic Syndrome

Idiopathic glomerular diseases can cause proteinuria and nephrotic syndrome 1–4 Idiopathic Membranous Nephropathy (iMN) Focal Segmental Glomerular Sclerosis (FSGS) Minimal [actharnephrology.com]

However, whether furosemide treatment affects massive proteinuria-induced TEC injury in patients with NS is unknown. [ncbi.nlm.nih.gov]

In the presence of stable renal function, a protein/creatinine ratio of more than 3.5 (mg/mg) can be taken to represent "nephrotic-range" proteinuria, and a ratio of less [doi.org]

Lupus Nephritis

METHOD: A retrospective study of proteinuria and renal function observed in LN patients with persistent proteinuria after adding a second immunosuppressant at 3, 6, 9 and [ncbi.nlm.nih.gov]

Surprisingly, proteinuria diminished after only 5 low-density lipoprotein (LDL) cholesterol apheresis sessions. [ncbi.nlm.nih.gov]

Both uMCP-1 and uTWEAK showed significant correlation with patients' rSLEDAI, 24-hour urine proteinuria (24hr UP), and anti-double-stranded DNA (anti-dsDNA) antibodies. [ncbi.nlm.nih.gov]

Congenital Vitamin B12 Deficiency

About half of people with Imerslund-Gräsbeck syndrome also have high levels of protein in their urine (proteinuria). [medlineplus.gov]

Code Info Category Info Clinical Information Publications/Journals Vitamin B12 deficiency anemia due to selective vitamin B12 malabsorption with proteinuria 2017 Billable [medicbind.com]

This applies to anemia: vegan's, vitamin B12 Deficiency (dietary), due to selective vitamin B12 malabsorption with proteinuria, and syndrome: imerslund's and imerslund-grasbeck [healthresearchfunding.org]

Chronic Glomerulonephritis

Plasma AM levels positively and urinary AM-levels negatively correlated with the degree of proteinuria. [ncbi.nlm.nih.gov]

RESULTS: Plasma adiponectin was much higher in patients with heavy proteinuria (38.8 +/- 27.8 microg/mL) than in patients with mild proteinuria (13.3 +/- 5.1 microg/mL, P [ncbi.nlm.nih.gov]

The present study compared the chronic effects of efonidipine and amlodipine on proteinuria in patients with chronic glomerulonephritis. [ncbi.nlm.nih.gov]

Amyloidosis

After one year, her symptoms of fatigue became worse, and her proteinuria increased. [ncbi.nlm.nih.gov]

AA, secondary to infection/inflammatory states, was identified in 4 patients with nephrotic-range proteinuria diagnosed on immunohistochemistry. [anzsnasm.com]

Following surgery, protein levels in the urine increased to the nephrotic range, and administration of tocilizumab was initiated, which resulted in resolution of the proteinuria [ncbi.nlm.nih.gov]

Systemic Lupus Erythematosus

We analyzed mean values of age, ESR, ESRp, CRP, ferritin and distribution of anti-dsDNA antibodies, C3 reduction, serositis, and erythrocyturia with proteinuria. [ncbi.nlm.nih.gov]

At present, the level of complement restored to normal, hematuria and proteinuria disappeared, and liver function returned to normal. [ncbi.nlm.nih.gov]

There were no relevant intercurrences until May 2015, when he presented with nephrotic range proteinuria (± 4 g/d). [ncbi.nlm.nih.gov]

Focal Embolic Glomerulonephritis

Nephrotic-range proteinuria is typically defined as greater than 3 to 3.5 g of protein in a 24-hour urine collection; however, not all persons with this range of proteinuria [aafp.org]

GFR usually returns to normal over 1 to 3 mo, but proteinuria may persist for 6 to 12 mo and microscopic hematuria for several years. [merckmanuals.com]

This disease frequently recurs after renal transplantation, and sometimes proteinuria recurs almost immediately. [enetmd.com]

Microscopic Polyangiitis

Seven patients manifested with hematuria and proteinuria, with renal histopathology of fibrinoid necrosis/exudation of the glomerular capillaries. [ncbi.nlm.nih.gov]

A 29-year-old woman with past medical history of hypertension was referred to our hospital for the evaluation of kidney dysfunction (serum creatinine 1.0 mg/dL), proteinuria [ncbi.nlm.nih.gov]

In the present study, most of the patients had renal lesions, with manifestations of hematuria and proteinuria. Mild-to-moderate proteinuria was frequently noted. [journals.plos.org]

Acute Kidney Injury

The main treatment, once proteinuria is established, is ACE inhibitor medications, which usually reduce proteinuria levels and slow the progression of diabetic nephropathy [en.wikipedia.org]

Red blood cell casts, dysmorphic red cells, moderate to severe proteinuria TABLE 6 Findings on Urinalysis in the Broad Categories of Acute Renal Failure Type of renal failure [aafp.org]

He suffered from proteinuria (4.3g/day), hematuria, hypertention (190/110mmHg), edema, oliguria and erysipelas. [ci.nii.ac.jp]

Benign Arteriolar Nephrosclerosis

Keywords: Hypertension, Nephropathy, Proteinuria, ESRD, Genetics 1. [file.scirp.org]

[…] indicated 27 glomerular proteinuria ; 15 mixed proteinuria. 12 These women, however, do not have proteinuria, edema, or convulsions. 13 Serum creatinine, creatinine clearance [sentencedict.com]

They were analyzed in relation to age at time of death, ante-mortem blood pressure level, results of glucose tolerance test and proteinuria. [jstage.jst.go.jp]

Membranoproliferative Glomerulonephritis

All patients with MPGN have proteinuria and/or hematuria. The degree of proteinuria is varied with a majority of individuals presenting in the nephrotic range (40-70%). [symptoma.com]

Lab tests Urinalysis reveals proteinuria and hematuria. [lecturio.com]

Such patients may have a bland urine sediment with a variable degree of proteinuria and elevation in serum creatinine. The diagnosis is made by renal biopsy [ 1 ]. [uptodate.com]

Hypokalemic Nephropathy

[…] kidneys with irregular outlines, features of papillary necrosis; increased incidence of urinary system cancers Lithium-associated nephropathy Treatment with lithium for ~15 y Proteinuria [empendium.com]

IgA nephropathy a chronic form marked by hematuria and proteinuria and by deposits of IgA immunoglobulin in the mesangial areas of the renal glomeruli, with subsequent reactive [medical-dictionary.thefreedictionary.com]

Proteinuria can be seen 5. Renal cysts can be noted 6. [nephronpower.com]

Systemic Amyloidosis

Findings We identified 101 patients with idiopathic Bence Jones proteinuria. [ncbi.nlm.nih.gov]

Abnormal exams: proteinuria (570 mg/24h), Bence-Jones proteinuria and clonal plasma cells (70%) found in myelogram. [ncbi.nlm.nih.gov]

Key words: AL Amyloidosis, Proteinuria, Hepatomegaly Advertisement Journal of Contemporary Medical Education SUBMIT YOUR ARTICLE NOW [scopemed.org]

Acute Glomerulonephritis

We describe a patient with FMF and E148Q mutation who presented with massive proteinuria, elevated serum creatinine level, and acute glomerulonephritis picture. [ncbi.nlm.nih.gov]

Despite corticosteroid treatment, his proteinuria persisted, and he developed end stage renal failure. [ncbi.nlm.nih.gov]

The macroscopic hematuria and proteinuria occurred on 5th day of G-CSF administration. [ncbi.nlm.nih.gov]

Lupus Nephritis WHO Class 6

Urine analysis showed 81.2% positive hematuria and 100% positive proteinuria. [brieflands.com]

Hematuria, proteinuria, nephrotic syndrome, hypertension, and decreased glomerular filtration rate are seen in nearly all patients with active class IV illness. [medicinenet.com]

High proteinuria may be related to podocytopathy since histological changes are not severe enough to explain this degree of proteinuria. [scirp.org]

Scleroderma with Renal Involvement

Most patients with proteinuria had toxicity from D-penicillamine. No explanations for proteinuria were found in 16 (2%) of this cohort. [jrheum.org]

EN UN ESTUDIO, LA CAUSA MÁS COMÚN DE PROTEINURIA FUE EL EMPLEO DE D-PENICILAMINA, CON EL DESARROLLO DE PROTEINURIA APARECIENDO EN UNA MEDIA DE 1.2 AÑOS DESPUÉS DEL INICIO [slideplayer.es]

Urinalysis commonly shows mild proteinuria and hematuria, with granular casts evident on microscopy. [sjkdt.org]

Renal Sarcoidosis

Under treatment with oral prednisone mean eGFR significantly improved from 38 ± 21 ml/min to 57 ± 26 ml/min and proteinuria decreased from 981 ± 304 mg/24 hrs to 176 ± 77 [ncbi.nlm.nih.gov]

Both patients presented with heavy proteinuria, hematuria, and renal failure. [ncbi.nlm.nih.gov]

On admission, the laboratory data suggested interstitial nephritis without proteinuria and hematuria, whereas a renal biopsy showed granulomatous interstitial nephritis and [ncbi.nlm.nih.gov]

Proximal Renal Tubular Acidosis

A 4-year-old girl was admitted to our hospital for investigation of short stature and proteinuria. [link.springer.com]

On arrival, laboratory test results were significant for hypokalemia, hyperchloremic metabolic acidosis, low uric acid concentration, positive urine anion gap, and proteinuria [ncbi.nlm.nih.gov]

Lai Tai 1995 Analysis of proteinuria in rats fed by hypopotassium diet. [researchmap.jp]

Muckle-Wells Syndrome

Renal involvement, in terms of proteinuria or renal insufficiency, can be observed in up to 25% of patients. [ncbi.nlm.nih.gov]

Interestingly, proteinuria decreased further to almost normal levels (around 200 mg/day) after the switch (Figure 1). [archivesofrheumatology.org]

Secondary amyloidosisis (see this term), revealed by persistent proteinuria, is a prominent feature affecting 25% of patients and can result in chronic renal insufficiency [orpha.net]

Orthostatic Proteinuria

Orthostatic proteinuria (postural proteinuria) is defined as normal urinary protein excretion during the night but increased excretion during the day, associated with activity [patient.info]

Proteinuria, Orthostatic Proteinuria Proteinuria is the most ominous finding in urinalysis suggestive of renal disease. [johnsarm.net]

[…] tubular proteinuria. [emedicine.medscape.com]

Rapidly Progressive Glomerulonephritis

[…] in sMer levels moving from low-grade to nephrotic-range proteinuria. [academic.oup.com]

It appears that severe hypertension and heavy proteinuria, while uncommon in anti-GBM disease, are consistent findings in RPGN form of FGN. [ncbi.nlm.nih.gov]

Rapidly progressive ("crescentic") glomerulonephritis is a primary glomerulonephritis, which produces nephritic syndrome (hematuria, oliguria, uremia, hypertension and mild proteinuria [pathologyatlas.ro]

Renal Amyloidosis

[…] with renal amyloidosis secondary to rheumatological diseases with varying degrees of proteinuria. [ncbi.nlm.nih.gov]

His proteinuria returned to <1 g/24 h with normalization of renal function and no significant proteinuria on periodic follow-up at 6-month and 1-year intervals. [ncbi.nlm.nih.gov]

KEYWORDS: Amyloidosis; gelsolin; proteinuria [ncbi.nlm.nih.gov]

Renal Infarction

In our Asian patients, the most common clinical characteristics were abdominal pain/tenderness, flank pain/tenderness, elevated serum LDH and proteinuria. [ncbi.nlm.nih.gov]

Compared with non-AKI patients, AKI occurrence was significantly correlated with degree of proteinuria (p CONCLUSIONS: AKI is often associated with acute renal infarction. [ncbi.nlm.nih.gov]

Urinalysis is not very helpful: patients with renal infarction may have hematuria, proteinuria, both, or neither. [epmonthly.com]