Presentation
Cardiovascular
There may be chest tightness involved depending on the severity. Although acute bronchitis is usually self-limiting with frequent bouts can lead to chronic bronchitis and possibly COPD and heart failure.
Musculoskeletal
The main symptom in this category would be muscle aches due to the chills and fever, and chest discomfort from the coughing.
Respiratory
Production of sputum that is usually white and clear, but can also be yellowish-grey or green in color, occurs. Occasionally, but rarely, it can be streaked with blood. There may also be shortness of breath due to the inflammation of the bronchial tubes and not being able to get enough air flow to the lungs. Tachypnea may be present. Productive cough of more than 5 days duration may already be suggestive of bronchitis [5].
Systemic
Sometimes there can be a slight fever and chills, as in flu like symptoms. If the acute bronchitis is from a bacterial infection, it possibly, but rarely can get into the blood stream and cause bacteremia.
Entire Body System
- Fever
Mild fever may be present, but high or prolonged fever is unusual and suggests influenza or pneumonia. On resolution, cough is the last symptom to subside and often takes 2 to 3 wk or even longer to do so. [merckmanuals.com]
Call your provider if you: Have a cough on most days, or have a cough that keeps returning Are coughing up blood Have a high fever or shaking chills Have a low-grade fever for 3 or more days Have thick, yellow-green mucus, especially if it has a bad smell [nlm.nih.gov]
- Fatigue
Sinus congestion Chest congestion Shortness of breath Wheezing Fatigue Body aches or chills Chest discomfort from coughing Here's a snapshot of the symptoms that distinguish acute bronchitis from chronic bronchitis, followed by more detailed information [verywell.com]
[…] production, cough, and symptoms of airway obstruction Clinical presentation patients with acute bronchitis or upper respiratory tract infection (URI) have considerable overlap in symptoms and signs symptoms may include cough (productive or nonproductive) fatigue [clinicaladvisor.com]
Some symptoms of acute bronchitis are: Chest discomfort Cough that produces mucus -- the mucus may be clear or yellow-green Fatigue Fever -- usually low-grade Shortness of breath that gets worse with activity Wheezing, in people with asthma Even after [nlm.nih.gov]
- Weakness
However, antibiotic prescribing practices for acute bronchitis/cough and hospitalizations for respiratory infections had a weak/moderate negative association. [ncbi.nlm.nih.gov]
Evidence supporting efficacy of routine use of other symptomatic treatments, such as antitussives, mucolytics, and bronchodilators, is weak. Antitussives should be considered only if the cough is interfering with sleep. [merckmanuals.com]
- High Fever
Call your provider if you: Have a cough on most days, or have a cough that keeps returning Are coughing up blood Have a high fever or shaking chills Have a low-grade fever for 3 or more days Have thick, yellow-green mucus, especially if it has a bad smell [nlm.nih.gov]
[…] doctor if your symptoms (sore throat, wheezing, coughing, chest congestion, body aches) last more than two weeks and/or if you experience any of the following symptoms: coughing or wheezing that worsens when you lie down or exercise shortness of breath a high [sharecare.com]
Mild fever may be present, but high or prolonged fever is unusual and suggests influenza or pneumonia. On resolution, cough is the last symptom to subside and often takes 2 to 3 wk or even longer to do so. [merckmanuals.com]
- Congestive Heart Failure
[…] and efforts to increase blood flow.[2] Congestive heart failure[edit] Congestive heart failure frequently presents with shortness of breath with exertion, orthopnea, and paroxysmal nocturnal dyspnea.[2] It affects between 1–2% of the general United States [en.wikipedia.org]
Most Common Differential Diagnosis of Acute Cough Acute bronchitis Allergic rhinitis Asthma Chronic obstructive pulmonary disease exacerbation Common cold Congestive heart failure exacerbation Gastroesophageal reflux disease Malignancy Pneumonia Postinfectious [aafp.org]
heart failure, or are receiving steroids Antibiotic therapy is recommended in patients with acute exacerbations of chronic bronchitis In stable patients with chronic bronchitis, long-term prophylactic therapy with antibiotics is not indicated. [emedicine.medscape.com]
Respiratoric
- Cough
Those taking ibuprofen had 9 days of frequent coughing vs. 11 for antibiotics and placebo, and also fewer total days of cough, but this wasn't statistically significant. [pulmccm.org]
In the combined data of trials in adults, there was a trend towards improvements regarding cough, productive cough and night cough as well as in daily cough severity scores in participants randomised to the beta2‐agonists. [doi.org]
Cough resolves within 2 wk in 75% of patients. Patients with persistent cough should undergo a chest x-ray. [merckmanuals.com]
This is indicated by the relationship between acute bronchitis and bronchial asthma. 3 Clinical presentation The first symptom of acute bronchitis is often a nonproductive cough (dry cough), which can be painful at high intensities. [flexikon.doccheck.com]
Participants given antibiotics were less likely to have a cough (four studies with 275 participants, RR 0.64, 95% CI 0.49 to 0.85; NNTB 6); have a night cough (four studies with 538 participants, RR 0.67, 95% CI 0.54 to 0.83; NNTB 7) and a shorter mean [epubs.rcsi.ie]
- Sputum
These observations suggest that sputum might be useful to monitor an inflammatory/immune response of the airway in acute infections. [ncbi.nlm.nih.gov]
In otherwise healthy people, green sputum is often present during viral infections. [pulmccm.org]
Sputum Gram stain and culture usually have no role. [merckmanuals.com]
At enrollment, sputum specimens were collected from all patients. Sputum amount was classified as scanty ( 50 cc/day), and sputum color was classified as white, yellow, brown, or green. [journals.plos.org]
Description respiratory tract infection with wheezing or coughing (with or without sputum) Incidence/prevalence sixth most common diagnosis made during family physician visits Possible risk factors underlying predisposition to bronchial reactivity during [clinicaladvisor.com]
- Productive Cough
The differences in presence of a productive cough at follow-up and MD of productive cough did not reach statistical significance.Antibiotic-treated patients were more likely to be unimproved according to clinician's global assessment (six studies with [epubs.rcsi.ie]
There were no significant differences regarding the presence of night cough, productive cough, or activity limitations at follow up, or in the mean duration of activity limitations. [ncbi.nlm.nih.gov]
Days of productive cough Comparison 6. [doi.org]
- Sore Throat
Chest tightness or pain Persistent fatigue Swelling of ankles, feet, and (sometimes) legs Acute Bronchitis The typical progression of bronchitis symptoms starts with a runny nose, sore throat, productive cough and low-grade fever. [verywell.com]
You should also call your doctor if your symptoms (sore throat, wheezing, coughing, chest congestion, body aches) last more than two weeks and/or if you experience any of the following symptoms: coughing or wheezing that worsens when you lie down or exercise [sharecare.com]
throat, nasal congestion, runny nose) Past medical history (PMH) ask about history of asthma Social history (SH) ask about smoking or other toxic inhalant exposures Physical General physical may have low-grade fever practitioner interpretation of common [clinicaladvisor.com]
The most common symptoms for acute bronchitis include cough, chest soreness, runny nose, feeling tired and achy, headache, chills, slight fever, and sore throat. [hopkinsmedicine.org]
As an alternative to an over-the-counter cough medicine, try making your own mixture of honey and lemon, which can help soothe a sore throat and ease your cough. [nhs.uk]
- Acute Cough
cough from acute bronchitis and the common cold. [pulmccm.org]
There is also little evidence that the routine use of beta2-agonists is helpful for adults with acute cough. These agents may reduce symptoms, including cough, in patients with evidence of airflow obstruction. [ncbi.nlm.nih.gov]
Cardiovascular
- Chest Pain
Wheezing and chest pain were associated with higher ABSS values, whereas irrelevant clinical variables were not. [ncbi.nlm.nih.gov]
Any time you have chest pain, you should call your doctor for advice. Chest pain can come from the heart as well as the lungs. [health.harvard.edu]
- Tachycardia
Pneumonia should be suspected in patients with tachypnea, tachycardia, dyspnea, or lung findings suggestive of pneumonia, and radiography is warranted. [ncbi.nlm.nih.gov]
[…] lung examination useful but not diagnostic wheezing, rhonchi, prolonged expiratory phase or other obstructive signs may be present but not essential Making the diagnosis no clear diagnostic criteria have been established cough in the absence of fever, tachycardia [clinicaladvisor.com]
[…] nasal congestion and runny nose Physical exam pulmonary auscultation wheezes rhonchi Studies Making the diagnosis based on history and physical exam imaging is not necessary Differential Pneumonia differentiating factor a cough with fever, tachypnea, or tachycardia [medbullets.com]
Multifocal atrial tachycardia, an arrhythmia that can accompany COPD, manifests as a tachyarrhythmia with polymorphic P waves and variable PR intervals. [msdmanuals.com]
Also, round 2/3 of women experience shortness of breath as a part of a normal pregnancy.[8] Cardiac tamponade presents with dyspnea, tachycardia, elevated jugular venous pressure, and pulsus paradoxus.[20] The gold standard for diagnosis is ultrasound [en.wikipedia.org]
Musculoskeletal
- Myalgia
The history should focus on type and length of symptoms, paying particular attention to worrisome systemic symptoms (such as fevers, myalgia, dyspnea) more commonly seen in pneumonia. [journals.lww.com]
Neurologic
- Confusion
In general practice, confusion surrounds the clinical diagnosis of acute bronchitis, especially when distinguishing it from asthma. [doi.org]
If the symptoms seems to be getting worse and you feel disoriented or confused. If the cough lasts for more than three weeks. [netdoctor.co.uk]
[…] that need medical attention immediately include:- Very severe cough that lasts over three weeks High fever for over three days Chest pains and rapid breathing rates of over 30 per minute Coughing up blood or sputum streaked with blood Drowsiness and confusion [news-medical.net]
If you become drowsy or confused. If a cough persists for longer than 3-4 weeks. If you have repeated (recurring) bouts of acute bronchitis. If any other symptom develops that you are concerned about. [patient.info]
Workup
- The first thing that the healthcare provider will be to ask questions regarding health history, such as smoking, second hand smoke or working in noxious inhalants.
- The healthcare provider will then listen to the lungs for air exchange and wheezing. They will listen for the presence of rhonchi, prolonged expiration and wheezing.
- The sputum can be tested for the presence of bacteria.
- Oxygen saturation percentage will be measured with a pulse oximeter.
- Chest x-ray may be done to rule out the presence of pneumonia.
- Blood tests may be performed.
- If necessary, pulmonary function tests and spirometry may be done, but these are performed when other diseases are suspected, such as COPD.
Treatment
The recommended treatment for acute bronchitis leans more towards palliative care, such as ibuprofen or acetaminophen for chills and fever, plenty of fluids and antitussives. Acute bronchitis is self-limiting and resolves on its own, although the cough may continue for a few more weeks. Antibiotics usually are not recommended as typically it is caused by a viral infection [6].
Antibiotic therapy may be given to high risk patients like those with asthma, smokers and Chronic Obstructive Pulmonary Disease (COPD), coupling it with bronchodilators significantly reduces hospital stay [7]. Studies further supports that using antibiotics in bronchitis cases can reduce hospital re-visits of patients from 76.8% to 27% in a 3 year period [8].
Occasionally a short-term dose of steroids may help with the inflammation of the bronchial tubes. Oral anti-inflammatory agents has been used to control the inflammation in acute bronchitis [9].
Prognosis
Acute bronchitis is almost always self limiting and clears up usually in 2 to 3 weeks without antibiotics. Some people, including infants, the elderly and those with pre-existing lung or cardiovascular diseases may be at higher risk of complications.
Although the main course of the acute bronchitis will subside quickly, the cough may continue for weeks after. If it lasts longer than a month, the physician may refer the patient to an otorhinolaryngologist, to see if something other than the bronchitis is causing the irritation to the lungs.
Complications
About one out of 20 people who experience acute bronchitis may develop a secondary infection which can become pneumonia.
Those that may be at risk for pneumonia are:
- Infants, babies and the elderly where there is diminished immunity and are more susceptible to a secondary infection.
- Patients with lung or heart conditions, these can include patients with COPD, heart failure patients and those with asthma.
- Diabetics may complicate to Acute Respiratory Distress Syndrome if bronchitis episodes remains too long [4].
- Smokers are more susceptible to develop chest infections, which can lead to a bacterial infection after having bronchitis.
Etiology
Acute bronchitis most often caused by a viral infection. The most common viruses are Rhinovirus, Influenza A virus, Influenza B virus, Parainfluenza virus, Corona virus and Respiratory Syncytial Virus [1]. The acute form of bronchitis can also be the result of inhaling things that can irritate the bronchial tubes such as smoke and toxic fumes, including ammonia. Smoking is one of the major causes of acute bronchitis.
Sometimes acute bronchitis can be caused by bacteria, such as Streptococcus. This can happen after a viral infection, such as a cold or the flu, which does not get better. Acute bronchitis can last 3 to 10 days, but the cough can last several weeks after the infection is gone.
Epidemiology
In the general population almost 5% will develop acute bronchitis in the US, the most occurrences happen during the fall and winter months. One of the top 5 reasons for children to see their Pediatrician is for lower respiratory infections, which include both acute and chronic bronchitis. Acute bronchitis is seen in males and females equally.
It is also seen in children under two years of age and then again between the ages of 9 and 15. Younger children exposed to second hand smoking and polycyclic aromatic hydrocarbons are more susceptible to develop bronchitis [2]. Elder patients are more prone to bronchitis because of their relatively low Forced Expiratory Volume (FEV), thus tend to accumulate more air and bacteria compared to the younger population [3].
Pathophysiology
Usually a viral infection, such as a cold or the flu, can turn into acute bronchitis, producing excess mucous and a cough lasting for several weeks in 50% of those affected, and 25% have the cough for a month or more.
An airway that is exposed to certain environmental agents, such as irritants or allergens, responds quickly to a cough and bronchospasm, followed by mucous production, edema and inflammation. This fact may explain why chronic bronchitis in children is actually asthma. The mucociliary clearance is a primary defense mechanism that helps protect the lungs from the damage caused by the inhalation of pollutants, pathogens and allergens.
Prevention
There is no way to prevent acute bronchitis from occurring but steps can be taken to reduce the risks. Smoking or being in a smoking environment can be a big trigger for those who have had episodes if bronchitis or whose pulmonary status is already compromised.
Receiving an annual flu shot is also recommended. Children receiving pneumonia and flu vaccines controls protracted bacterial bronchitis and prevents recurrent coughing [10]. Avoiding the inhalation of noxious irritants, especially in enclosed areas.
Summary
Viruses, bacteria, and other agents can cause inflammation of the inner lining of the bronchial tubes, a condition which is referred to as acute bronchitis. Production of mucus causes one of the main symptoms - cough. Often acute bronchitis follows an upper respiratory infection.
Patient Information
Acute bronchitis is an inflammation of the bronchial tubes, the major airways into the lungs, which may be usually caused by bacteria and viruses.
Common signs and symptoms are:
Most cases of bronchitis are caused by a viral infection and resolve themselves within a few days to weeks.
References
- Albert RH. Diagnosis and treatment of acute bronchitis. Am Fam. Physician. 2010; 82(11):1345-50 (ISSN: 1532-0650)
- Ghosh R; Topinka J; Joad JP; Dostal M; Sram RJ; Hertz-Picciotto I. Air pollutants, genes and early childhood acute bronchitis. Mutat Res. 2013; 749(1-2):80-6 (ISSN: 0027-5107)
- Jivcu C, Gotfried M. Gemifloxacin use in the treatment of acute bacterial exacerbation of chronic bronchitis.Int J Chron Obstruct Pulmon Dis. 2009;4:291-300.
- Homsi S; Milojkovic N; Alawad B; Homsi Y. Prolonged period of acute bronchitis with late progression to acute respiratory distress syndrome as possible result of influenza A (H1N1) virus infection. J Ark Med Soc. 2012; 109(4):62-4 (ISSN: 0004-1858)
- Wenzel RP, Fowler AA 3rd. Clinical practice. Acute bronchitis. N Engl J Med. Nov 16 2006;355(20):2125-30.
- Gonzales R, Steiner JF, Sande MA. Antibiotic prescribing for adults with colds, upper respiratory tract infections, and bronchitis by ambulatory care physicians. JAMA. Sep 17 1997;278(11):901-4.
- Kroening-Roche JC; Soroudi A; Castillo EM; Vilke GM. Antibiotic and bronchodilator prescribing for acute bronchitis in the emergency department.J Emerg Med. 2012; 43(2):221-7 (ISSN: 0736-4679)
- Roth S; Gonzales R; Harding-Anderer T; Bloom FJ; Graf T; Stahl MS; Maselli JH;
- Metlay JP. Unintended consequences of a quality measure for acute bronchitis. Am J Manag Care. 2012; 18(6):e217-24 (ISSN: 1936-2692)
- Llor C; Moragas A; Bayona C; Morros R; Pera H; Cots JM; Fernández Y; Miravitlles M; Boada A. Effectiveness of anti-inflammatory treatment versus antibiotic therapy and placebo for patients with non-complicated acute bronchitis with purulent sputum. The BAAP Study protocol.BMC Pulm Med. 2011; 11:38 (ISSN: 1471-2466)
- Priftis KN; Litt D; Manglani S; Anthracopoulos MB; Thickett K; Tzanakaki G; Fenton P; Syrogiannopoulos GA; Vogiatzi A; Douros K; Slack M; Everard ML. Bacterial bronchitis caused by Streptococcus pneumoniae and nontypable Haemophilus influenzae in children: the impact of vaccination.Chest. 2013; 143(1):152-7 (ISSN: 1931-3543)