UCTD was considered present when serum autoantibodies were present and symptoms or signs suggested CTD. The relationship between UCTD and NSIP histology was evaluated. [ncbi.nlm.nih.gov]

• Pathologist

  Three clinicians, two radiologists, and two pathologists reviewed 58 consecutive cases of suspected idiopathic interstitial pneumonia. [ncbi.nlm.nih.gov]

• Fever

  We describe a case of a woman who presented with a persistent cough, general fatigue, and a fever. Interstitial lung disease was rapidly progressive and resistant to high-dose steroid therapy. [ncbi.nlm.nih.gov]

  We have recently experienced an epidemic of yellow fever (YF) in Brazil. [journals.plos.org]

  Staphylococcus species Teaching Image Question 2 A 6-year-old immigrant boy from Bangladesh presents with fever and rash. The fever started 3 days ago followed by a rash which started on the head and spread to the rest of the body. [roshreview.com]

  […] fibrosing alveolitis ICD-9-CM Volume 2 Index entries containing back-references to 516.30 : Alveolitis Pneumonia (acute) (Alpenstich) (benign) (bilateral) (brain) (cerebral) (circumscribed) (congestive) (creeping) (delayed resolution) (double) (epidemic) (fever [icd9data.com]

• Aspiration

  A new chapter on terrorism and disaster medicine has been added and new contributors have rewritten the chapters on preoperative pulmonary evaluation, aspiration pneumonia, the lung in immunocompromised hosts, staphylococcal and streptococcal pneumonias [books.google.com]

  […] chronic GORD reflux aspiration Smoking is a risk factor Genetic factors are probably important Usually presents in middle age – older (>55 years old) patients Clinical Presentation Insidious onset Dry/non-productive cough Worsening shortness of breath [dundeemedstudentnotes.wordpress.com]

  Importance of diffuse aspiration bronchiolitis caused by chronic occult aspiration in the elderly. Chest 1996; 110:1289-1293. [siicsalud.com]

  Aspiration induced pulmonary disease is bronchiolocentric and cicatricial but usually lacks lobular interstitial inflammation while the presence of foreign material and often eosinophils can be helpful discriminators. [nature.com]

  Chronic eosinophilic pneumonia Bronchoalveolar cell carcinoma Aspiration pneumonia Pulmonary infarction Lymphoma The images on the left show the similarities between chronic eosinophilic pneumonia and organizing pneumonia. [radiologyassistant.nl]

• Exertional Dyspnea

  The history and results of physical and laboratory evaluations have little diagnostic accuracy for IPF. 48 In all chronic forms of idiopathic interstitial pneumonia, patients usually present with progressive dyspnea on exertion and dry cough. [archinte.ama-assn.org]

  Most patients present with a gradual onset (often >6 mo) of exertional dyspnea and/or a nonproductive cough. Approximately 5% of patients have no presenting symptoms when idiopathic pulmonary fibrosis is serendipitously diagnosed. [emedicine.medscape.com]

• Respiratory Insufficiency

  Inclusion criteria include:  Clinical criteria: chronic respiratory insufficiency manifestations including dyspnea/tachypnea, cough, and cyanosis during exercise or at rest  Radiological criteria: characteristic chest High-Resolution Computed Tomography [epidemiologie-france.aviesan.fr]

  In a second patient (B), with respiratory insufficiency and severe reduction of DLCO (39 %), the UIP pattern was again diagnosed by CT examination. C and D show diffuse honeycombing, which massively involves the basal regions of lower lobes. [link.springer.com]

• Chronic Cough

  Cough in Idiopathic Pulmonary Fibrosis With Thalidomide Completed NCT00600028 Phase 3 Thalidomide;Placebo 16 Open Label Extension Study in Patients With Idiopathic Pulmonary Fibrosis Who Completed Protocol AC-052-321/ BUILD 3 / NCT00391443 Completed [malacards.org]

• Diarrhea

  A brief discussion with his pediatrician confirms your suspicion of an invasive bacterial diarrhea; a stool culture was positive for Shigella. Which of the following statements is true regarding this condition? A. [roshreview.com]

  Chronic, severe vomiting or diarrhea and other causes of dehydration. This causes your body to lose electrolytes, such as sodium, and also increases ADH levels. Drinking too much water. [mayoclinic.org]

  Most Common Adverse Reactions The most common adverse reactions occurring more frequently (>3%) on Adempas than placebo were headache (27% vs 18%), dyspepsia/gastritis (21% vs. 8%), dizziness (20% vs 13%), nausea (14% vs 11%), diarrhea (12% vs 8%), hypotension [prnewswire.com]

• Regurgitation

  […] following: Fine bibasilar inspiratory crackles (Velcro crackles): Noted in most patients Digital clubbing (25-50%) Pulmonary hypertension at rest (20-40%) [4] : Loud P2 component of the second heart sound, a fixed split S2, a holosystolic tricuspid regurgitation [emedicine.medscape.com]

• Osteoporosis

  Oxygen supplementation should be instituted in all patients with significant desaturation ( IPF comorbidities IPF comorbidities include pulmonary hypertension, coronary artery disease, obstructive sleep apnea, GERD, osteoporosis, hypogonadism, depression [clinicaladvisor.com]

Studies have shown that cryobiopsy can provide a definitive diagnosis in many patients undergoing workup for IIP, eliminating the need for surgical lung biopsy. [clinicaladvisor.com]

It is possible that bronchiolocentric interstitial pneumonia represents a form of chronic hypersensitivity pneumonitis for which the inhalational stimulus has not been identified despite our extensive workup for this condition. [nature.com]

See Workup for more detail. Management The optimal medical therapy for the treatment of idiopathic pulmonary fibrosis has yet to be identified. [emedicine.medscape.com]

• Neutrophilia

  Baseline BAL neutrophilia predicts early mortality in idiopathic pulmonary fibrosis. Chest. 2008 Jan. 133(1):226-32. [Medline]. Kinder BW, Brown KK, McCormack FX, et al. [emedicine.medscape.com]

  A number of parameters at the time of diagnosis have been proposed as predictors of worse survival in IPF: increasing age, male sex, degree of dyspnea, smoking history, severity of lung function and radiographic abnormality, neutrophilia or eosinophilia [dx.doi.org]

Although pulmonary (67)Ga uptake significantly decreased after treatment (P = 0.001), there was no correlation between either initial (67)Ga uptake or change in (67)Ga uptake on treatment and 1-y prognosis. [ncbi.nlm.nih.gov]

steroids Associations: Sjögren, AIDS Treatment: smoking cessation Mortality 30% at 10 yearsTreatment: ventilation/steroids Multiple basal predominant Treatment: steroids Upper lung predominant faint Treatment: smoking cessationDiffuse symmetric basal [slideshare.net]

Novel treatments (pirfenidone and nintedanib) are available but choice of treatment, duration and impact on a real life scale are unknown. 6 Classification of IIPs (ATS/ERS 2013) 3 References: Travis WD, Costabel U, Hansell DM, King TE, Lynch DA. [swissiip.ch]

Females of reproductive potential: Exclude pregnancy before the start of treatment, monthly during treatment, and 1 month after stopping treatment. [prnewswire.com]

In patients with IPF or fibrotic NSIP, pulmonary (67)Ga scintigraphy may be useful for predicting response to therapy and prognosis. [ncbi.nlm.nih.gov]

Predicting prognosis in the individual patient is challenging but various clinical and radiologic variables have been identified. [doi.org]

As the name implies, the etiology is unknown. In the more severe forms of IIP, such as idiopathic pulmonary fibrosis and acute interstitial pneumonia, no effective therapies have been identified. [ncbi.nlm.nih.gov]

Certain conditions have both an underlying etiology and multiple body system manifestations due to the underlying etiology. [icd10coded.com]

[…] such as connective tissue diseases and hypersensitivity pneumonia IPF was previously called chronic interstitial pneumonitis or cryptogenic fibrosing alveolitis Sites Bottom of lower lobes of bilateral (or "bibasilar") lung Pathophysiology / etiology [pathologyoutlines.com]

Jump to: navigation, search Idiopathic Interstitial Pneumonia Microchapters Home Patient Information Overview Historical Perspective Classification Pathophysiology Causes Differentiating Idiopathic interstitial pneumonia from other Diseases Epidemiology [wikidoc.org]

SETTING: Although the incidence and prevalence of idiopathic interstitial pneumonia (IIP) and idiopathic pulmonary fibrosis (IPF) have been assessed in Western countries, their epidemiology has not been analysed in Asian countries, including the Republic [ncbi.nlm.nih.gov]

COP: Epidemiology and outcomes The initial name of COP was bronchiolitis obliterans with organizing pneumonia (“BOOP”). [clinicaladvisor.com]

Idiopathic Interstitial Pneumonia Aka: Idiopathic Pulmonary Fibrosis, Usual Interstitial Pneumonia, Desquamative Interstitial Pneumonia, Respiratory Bronchiolitis, RB-ILD, Acute Interstitial Pneumonia, Hamman-Rich Disease, Nonspecific Interstitial Pneumonia Epidemiology [66.199.228.237]

Contents Complications and Discontinuation 339 Oxygen Therapy and Toxicity 345 ProtocolDriven Care in Respiratory Therapy 351 Epidemiology Natural History 357 Prophylaxis 364 Chronic Thromboembolic Pulmonary Hypertension 375 Unusual Forms of Embolism [books.google.com]

New insight into the pathophysiology of idiopathic pulmonary fibrosis suggests a distinctly fibroproliferative process, and antifibrotic therapies show promise. [ncbi.nlm.nih.gov]

Jump to: navigation, search Idiopathic Interstitial Pneumonia Microchapters Home Patient Information Overview Historical Perspective Classification Pathophysiology Causes Differentiating Idiopathic interstitial pneumonia from other Diseases Epidemiology [wikidoc.org]

Since IP itself is likely a risk factor for PP, prevention of BPF is important for patients with IP, as it can lead to PP. [ncbi.nlm.nih.gov]

Prevention of bacterial endocarditis. ‎ Page 303 - American Thoracic Society. Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. ‎ [books.google.com]

Prevention The following measures may help you prevent hyponatremia: Treat associated conditions. Getting treatment for conditions that contribute to hyponatremia, such as adrenal gland insufficiency, can help prevent low blood sodium. [mayoclinic.org]

Can interstitial lung disease be prevented? Interstitial lung disease can be prevented only to the extent that its individual causes may be prevented. [medicinenet.com]