Presentation
Paraneoplastic neurological disorders are uncommon presentations of head and neck cancers. We present a case of a 68-year-old male patient who presented with dizziness, nausea and memory problems. [ncbi.nlm.nih.gov]
Entire Body System
- Movement Disorder
Dyskinesia or abnormal, uncontrolled movement is a common symptom in many movement disorders. Dyskinesia also includes tremors. [astermedcity.com]
These impairments include multifocal and global cerebral ischemia, cerebral hemorrhages, infarctions, optic neuropathy, cerebral atrophy, cognitive impairments, and mood and movement disorders. [ncbi.nlm.nih.gov]
This three-day conference covered all functional disorders in neurology, including: Functional movement disorders, non-epileptic seizures, functional speech/visual/cognitive/dizziness Aetiology and mechanism including neurophysiology/fMRI Treatment, ethics [fnd2017.org]
Movement Disorders The Emory Parkinson’s Disease and Movement Disorders Program faculty provide internationally recognized expertise in Parkinson's disease, Huntington's disease, dystonia, tremor, tic disorders and other movement disorders. [emoryhealthcare.org]
- Falling
For the prevention of falls, individual fall risk assessment is the necessary first step. [ncbi.nlm.nih.gov]
Symptoms The signs of NMO fall into two categories. See your doctor if you have any of these symptoms: Optic neuritis: inflammation of the optic nerve (this carries information from your eye to your brain). [webmd.com]
(high-strung) متوتر Our baby is so nervous that he can't fall asleep easily. nervous adj adjective : Describes a noun or pronoun--for example, "a tall girl," "an interesting book," "a big house." [wordreference.com]
Parkinson’s disease Gait Flexed/stooped posture Difficulty defending balance Difficulty initiating walking (‘freezing’) Steps small and shuffling Festinant Normal arm swing lost Risk of falls 24. Posture 25. [slideshare.net]
- Difficulty Walking
Signs and symptoms that affect body movement and function may include: Weakness or paralysis Abnormal movement, such as tremors or difficulty walking Loss of balance Difficulty swallowing or feeling "a lump in the throat" Seizures or episodes of shaking [mayoclinic.org]
Symptoms include seizures, limb weakness, difficulty walking, speech impairments and swallowing difficulties, strange sensations, learning impairments, challenging behaviors, or vision and hearing impairments. [childneurologyfoundation.org]
Symptoms may include: problems with learning and memory, including amnesia forgetfulness poor coordination difficulty walking Alcoholic neuropathy This condition occurs when the peripheral nerves are damaged by too much alcohol. [healthline.com]
- Weight Loss
Center | Bascom Palmer Eye Institute Font Size Group 30 Group 30 Contrast logo Menu Search University of Miami Health System Close Search Find a Doctor Treatments Page 1 Featured Treatments For Allergy and Immunology Arthritis (Rheumatology) Bariatrics (Weight [umiamihealth.org]
loss, fatigue or unexplained anaemia. 1.4.2 Do not use serological testing alone to determine whether gluten has been excluded from the person's diet. 1.4.3 Offer an annual review to people with coeliac disease. [nice.org.uk]
Mental contrasting with implementation intentions (MCII) improves physical activity and weight loss among stroke survivors over one year. Rehabil Psychol. 2017 Nov;62(4):580-590. doi: 10.1037/rep0000104. [kliniken-schmieder.de]
Weight loss, dehydration, and respiratory compromise may also be associated with dysphagia. [nature.com]
Malnutrition and weight loss are frequently observed in patients with IBD, especially CD. [scielo.mec.pt]
- Acute Intermittent Porphyria
Acute intermittent porphyria can give rise to acute psychosis, often in association with abdominal pain. [doi.org]
Gastrointestinal
- Muscle Rigidity
Muscle rigidity Tremors and seizures Back pain which radiates to the feet, toes, or other parts of the body Muscle wasting and slurred speech New language impairment (expression or comprehension) The symptoms of a nervous system disorder may look like [hopkinsmedicine.org]
Parkinson's produces many common symptoms, including tremor; muscle rigidity or stiffness of the limbs; gradual loss of spontaneous movement, often leading to decreased mental skill or reaction time, voice changes or decreased facial expression; gradual [aans.org]
- Fecal Incontinence
difficulty urinating, and more frequent urination fecal incontinence or constipation A person with NMO may have just one mild attack of ON and one episode of TM, recover completely, or almost completely, and have no more relapses ever. [medicalnewstoday.com]
Cardiovascular
- Hypertension
Subnormal scores were found in 76 subjects (5.9%), associated with age, education, hypertension, severe white matter hyperintensities, and distribution and number of MBs. [ncbi.nlm.nih.gov]
Attention Deficit-Hyperactivity Disorder Autism Spectrum Disorder Autonomic Dysfunction B Back Pain Barth Syndrome Batten Disease Becker’s Myotonia Behcet’s Disease Bell’s Palsy Benign Essential Blepharospasm Benign Focal Amyotrophy Benign Intracranial Hypertension [neurosciencenews.com]
In the hypertensive population of Framingham, the ratio of myocardial infarction to stroke was two in men and one in women, whereas it was six in men and three in women who were not hypertensive. 5 The study also showed in men that in the presence of [jnnp.bmj.com]
[…] of hepatosplenomegaly, radiography and bone scintigraphy to detect bone lesions and complications, osteodensitometry for the evaluation of osteopenia of the lumbar spine and femoral neck, and cardiac ultrasound for the detection of pulmonary arterial hypertension [orpha.net]
- Hypotension
[…] hour sleep–wake disorder Nonverbal learning disorder O [ edit ] O'Sullivan–McLeod syndrome Occipital Neuralgia Occult spinal dysraphism sequence Ohtahara syndrome Olivopontocerebellar atrophy Opsoclonus myoclonus syndrome Optic neuritis Orthostatic hypotension [en.wikipedia.org]
Orthostatic hypotension can be improved by prescribing drugs that raise blood pressure. As MSA progresses, the benefits of medication lessen. [aans.org]
On day 7, the patient’s heart rate was slower than 40 beats per minute, and he was hypotensive. A CT scan showed edema of the brain stem, hippocampi, and temporal lobes. On day 8, he had bilateral dilated and light-unreactive pupils. [nejm.org]
Neuropathy, defined as the presence of bilateral impaired vibration perception, was present in one study in 17% of diabetic patients aged 20-59, 42% in patients aged 60-69, and 10% of patients aged 70 or over. 134 Autonomic neuropathy can lead to postural hypotension [jnnp.bmj.com]
Eyes
- Visual Impairment
There are several possible complications of NMO including: Visual impairment or blindness Paralysis or weakness of one or more limb Stiffness or muscle spasms Loss of bowel or bladder control Depression Fatigue Living with neuromyelitis optica Disability [hopkinsmedicine.org]
It may include impairment of cognition, such as impairments in “language,” (visual and spatial) "awareness," “attention” and memory. [richardsonthebrain.com]
The patient was severely malnourished (BMI: 10.93 kg/m2) with muscular atrophy and complained of visual impairment. On neurologic evaluation, diplopia and limitation of eye movements were detected. [scielo.mec.pt]
Individuals with cerebral palsy may also experience seizures, abnormal speech, hearing and visual impairments, and mental retardation. Children with cerebral palsy may not be able to walk, talk, eat, or play in the same ways as most other children. [firstsigns.org]
Musculoskeletal
- Torticollis
Focal dystonias involve only one body location, most commonly the neck (spasmodic torticollis), eyelids ( blepharospasm ), lower face ( Meige syndrome ) or hand ( writer's cramp or limb dystonia ). [aans.org]
They may be confined to one part of the body; for example, spasmodic torticollis affects only the neck, while Meige's syndrome distorts the face. These chronic, slowly progressive disorders are often painful and can cause mild to severe disability. [nap.edu]
Psychiatrical
- Visual Hallucination
Neurologic characteristics include fluctuating cognitive ability, visual hallucinations, spontaneous parkinsonism, sleep disturbance, and reduced ability to perform activities of daily living. [nature.com]
The anatomy of conscious vision: an fMRI study of visual hallucinations. Nat Neurosci 1998 ; 1 : 738 –42. Cummings JL, Mega MS. Neuropsychiatry and behavioural neuroscience. [doi.org]
Neurologic
- Dysarthria
Lee Silverman Voice Therapy – LSVT; Stardust Dysarthria Management Programme.) If you are already involved in a special programme (e.g. LSVT), you may wish to talk to the therapist about that. [helpwithtalking.com]
For a more detailed explanation of Dysarthria and the compensatory strategies go to our online Downloads Section, or the Dysarthria page. Dysphonia Dysphonia is a hoarseness, weakness or loss of voice. [icommunicatetherapy.com]
Dysarthria A speech disorder resulting from weakness, slowness, or poor coordination of speech. [iup.edu]
Terms Neurological Voice Disorders: Voice problems caused by abnormal control, coordination, or strength of voice box muscles due to an underlying neurological disease such as: stroke, Parkinson’s disease, multiple sclerosis, myasthenia gravis, or ALS Dysarthria [voicefoundation.org]
- Nystagmus
Migraine, tachycardia, intention tremor, nystagmus and cervical dystonia were observed in isolated individuals. [ncbi.nlm.nih.gov]
[…] columns of the spinal cord; characterized by muscular weakness and abnormal gait; occurs in children hereditary cerebellar ataxia nervous disorder of late childhood and early adulthood; characterized by ataxic gait and hesitating or explosive speech and nystagmus [vocabulary.com]
Nystagmus (gaze-evoked and direction-changing) subsequently appeared. The headache ceased. The results of blood tests were normal. [nejm.org]
Symptoms may include: unsteady walk tremor in the trunk of the body jerky movements of the arms or legs slurred speech rapid movements of the eyes, called nystagmus Alcoholic myopathy Alcohol affects muscle fibers causing alcoholic myopathy. [healthline.com]
- Agitation
عُصاب ) volume_up neurosis {noun} Similar translations Similar translations for "اضْطِراب عَصَبيّ" in English اضْطِراب noun English unrest turmoil upheaval commotion disorder disruption muddle ructions turbulence turbulence unease whirl disorder stir agitation [en.bab.la]
Symptoms of Degenerative Diseases: Anxiety Apathy Agitation Inhibition loss Memory loss Forgetfulness Constant mood changes Brain injuries Many cases of a neurological disorder are related to injuries to the brain. [vinnhospital.com]
[…] diseases include: Huntington’s disease ALS (amyotrophic lateral sclerosis), or Lou Gehrig’s disease Parkinson’s disease all forms of dementia Some of the more common symptoms of neurodegenerative diseases include: memory loss forgetfulness apathy anxiety agitation [healthline.com]
Treatments would also be welcome that reduced agitation or antisocial behavior in Alzheimer 's patients—behaviors that are not only unsafe but that also reduce caregivers ' ability to help patients. [nap.edu]
- Apathy
Symptoms of Degenerative Diseases: Anxiety Apathy Agitation Inhibition loss Memory loss Forgetfulness Constant mood changes Brain injuries Many cases of a neurological disorder are related to injuries to the brain. [vinnhospital.com]
FvFTD, exemplified here, often presents first to a psychiatrist, typically with a blunting of emotions, apathy, and egocentricity. [doi.org]
[…] neurodegenerative diseases include: Huntington’s disease ALS (amyotrophic lateral sclerosis), or Lou Gehrig’s disease Parkinson’s disease all forms of dementia Some of the more common symptoms of neurodegenerative diseases include: memory loss forgetfulness apathy [healthline.com]
- Paresthesia
Occult spinal dysraphism sequence Ohtahara syndrome Olivopontocerebellar atrophy Opsoclonus myoclonus syndrome Optic neuritis Orthostatic hypotension Otosclerosis Overuse syndrome P [ edit ] Palinopsia Pantothenate kinase-associated neurodegeneration Paresthesia [en.wikipedia.org]
She continued to experience lower extremity weakness and paresthesias as well as back and leg pain. No diagnosis was made. The patient had been unable to work since her symptoms began. Ms. [ajp.psychiatryonline.org]
Workup
Screening for vitamin B 12 deficiency, thyroid dysfunction, and syphilis must be completed in the workup for Alzheimer's disease in order to rule out potential other causes of dementia. [nature.com]
Treatment
After an 8-day hospital course, which included several different treatment modalities including plasmapheresis, the patient was discharged after making a complete recovery. [ncbi.nlm.nih.gov]
Health System Should Prepare for Future Alzheimer's Treatments The U.S. health care system isn't ready to meet demand for a breakthrough Alzheimer's treatment. [rand.org]
This comprehensive text reference seeks to assist physicians with treatment by providing an easy-to-use compendium covering the treatment and management of all neurological diseases along with details on the natural course of these diseases. [elsevier.com]
Prognosis
Definition Treatment Prognosis Clinical Trials Organizations Publications Definition Neuromyelitis optica (NMO) is an autoimmune disease of the central nervous system (CNS) that predominantly affects the optic nerves and spinal cord. [ninds.nih.gov]
Prognosis The prognosis is variable: patients may recover completely from individual attacks, but residual neurological deficits are common and sometimes severe. [orpha.net]
The new findings advance current understanding of the mechanisms involved in this disease, and offer the possibility of identifying markers of the condition and patients’ prognosis. [healtheuropa.eu]
This paper is expected to contribute to the development of an analytical platform to discover biomarkers that will aid diagnosis, prognosis, and treatment of neurodegenerative disorders. [dbpia.co.kr]
Drug-Resistant Seizures Often Take Years to Develop January 2003 press release on new findings regarding the prognosis of partial epilepsy. [webmd.com]
Etiology
This article addresses etiology, clinical manifestations, importance of early diagnosis and pharmacological treatment. Nursing interventions for the TS patient will also be discussed. [ncbi.nlm.nih.gov]
Etiology Etiology is unknown but NMO is believed to be an autoimmune disease associated with autoantibodies to aquaporin-4. [orpha.net]
Epidemiology
This hypothesis can explain many aspects of RLS, including symptoms as well as epidemiological findings. [ncbi.nlm.nih.gov]
Epidemiological data regarding the neurological conditions is limited in Pakistan. [bmcneurol.biomedcentral.com]
Part 2: Epidemiology, clinical presentation, radiological and laboratory features, treatment responses, and long-term outcome Journal of Neuroinflammation 2016; 13:280. Jarius et al. [rarediseases.org]
Pathophysiology
Abstract OBJECTIVE: Affective symptoms influence health status (health-related quality of life) in functional neurological disorder (FND), and the salience network is implicated in the pathophysiology of FND and mood/anxiety disorders. [ncbi.nlm.nih.gov]
DESIGN: This is an observational diagnostic study of multiple neurological diseases and their pathophysiology. [clinicaltrials.gov]
Development of new imaging methods help us understand the pathophysiology of aneurysm development and the risk of rupture. [esciencecentral.org]
B cells in the pathophysiology of autoimmune neurological disorders: A credible therapeutic target. Pharmacol Ther. 2006;112(1):57-70. Wingerchuk D. Neuromyelitis optica. Int MS J. 2006; 13:42-50. [rarediseases.org]
Prevention
Research on prevention is still being developed, but health-promoting lifestyle choices can decrease one’s risk of these diseases. A nutritious diet, avoidance of tobacco, and increased physical activity all can qualify as preventative measures. [ncdalliance.org]
However, reducing the number of attacks with immunosuppressive medications may help prevent with accumulation of disability. [ninds.nih.gov]
Although innominate artery transection for innominate artery compression of the trachea is recently used for prevention of life-threatening complications (e.g. massive bleeding and obstructive apnoea) in patients with neurological disorders, pre-existing [ncbi.nlm.nih.gov]
It is society’s responsibility to invest in preventive and palliative care for such patients and try to reintegrate them into public life. Reaching for this level of inclusiveness is what defines progress. [blog.thryveinside.com]