[…] pityriasis amiantacea. [31] Atypical symptoms Pruritus may or may not be present in a patient. [dx.doi.org]

Atypical presentations of pityriasis rosea: Case presentations. J Eur Acad Dermatol Venereol. 2005; 19 :120–6. [ PubMed ] [ Google Scholar ] 20. Bernardin RM, Ritter SE, Murchland MR. Papular pityriasis rosea. [ncbi.nlm.nih.gov]

Clinical Presentation The initial presentation of the disease is in most cases marked by the appearance of a herald patch, a well-circumscribed erythematous patch multiple centimeters in diameter with mild central clearing and depression. [pedclerk.bsd.uchicago.edu]

In children, presentation can be atypical or inverse, and the course is typically milder. About one in four people with PR have mild to severe symptomatic itching. [en.wikipedia.org]

It presents as multiple papules which occur along with classic patches and plaques. [statpearls.com]

• Eruptions

  Progression to the chronic lichenoid form occasionally occurs. pityriasis al´ba a chronic condition with patchy scaling and hypopigmentation of the skin of the face. chronic lichenoid pityriasis a chronic brown to red-brown scaly macular eruption, seen [medical-dictionary.thefreedictionary.com]

  Stanford, Pityriasis Rosea-Like Drug Eruptions, Cutaneous Drug Eruptions, 10.1007/978-1-4471-6729-7_13, (135-140), (2015). Robert A. Schwartz and W. [doi.org]

  Pityriasis rosea • mild, common, self-limited eruption; may be due to human herpesvirus 7 (HHV-7) • suspected infectious etiology due to: occurrence primarily in adolescents and young adults in the spring and fall; recurrence is uncommon • eruption typically [dermweb.com]

  Drug eruptions. Erythema migrans. Lichen planus. Polymorphic eruption of pregnancy. Secondary syphilis. Kaposi's sarcoma. HIV seroconversion (usually associated with a febrile, flu-like illness). [patient.info]

• Eczema

  However, does Eczema Free Forever work? Is it really worth the money? Eczema Free Forever discount. [enhance-itn.eu]

  It has been given names like "prurigo Besnier," "neurodermitis," "endogenous eczema," "flexural eczema," "infantile eczema," and "prurigo diathésique". [findzebra.com]

  Guttate psoriasis, secondary syphilis, cutaneous lupus erythematosus, capillaritis, pityriasis versicolor, nummular eczema, and cutaneous T-cell lymphoma are important to consider in the differential diagnosis of pityriasis rosea. [ncbi.nlm.nih.gov]

• Skin Rash

  Last updated June 12, 2017 Pityriasis Rosea is a benign, skin disorder characterized by the presence of skin rashes. [dovemed.com]

  The rash starts with a single large patch called a herald patch. After several days, more skin rashes will appear on the chest, back, arms, and legs. [nlm.nih.gov]

  Skin rashes can sometimes be very difficult to diagnose. A variety of common skin conditions can manifest as a skin rash. Skin rashes apart from the medical aspect are associated with social stigma as well. [fever.pk]

• Pruritus

  Except for mild pruritus, pityriasis rosea is asymptomatic. The lesions disappear within two months, often causing postinflammatory hyperpigmentation or hypopigmentation. [amboss.com]

  The aim of treatment is thus mainly to relieve pruritus, not to modify the course of the disease. For children with little or no pruritus and a limited number of lesions, no treatment is generally required. [plasticsurgerykey.com]

  The peak incidence that we saw in April and May has been described in the literature. 6 Pruritus has been reported in 25% to 94% of patients. 6, 7 Our finding of pruritus in 90% of patients fits into this broad range. [jamanetwork.com]

  However, some dermatologists use prednisone (0.5-1 mg/kg/day for 7 days) in selected patients with severe pruritus, vesicular lesions, or the potential for significant postinflammatory hyperpigmentation, to suppress both pruritus and the exanthem. [dailyrounds.org]

• Papulosquamous Rash

  As the rash and itching did not improve, mother brought him to the pediatric clinic. On examination, he had a papulosquamous rash mainly on his trunk with a Christmas tree pattern [Figure 1]. [e-ijd.org]

  It is characterized by an initial herald patch, followed by the development of a diffuse papulosquamous rash. The herald patch often is misdiagnosed as eczema. [aafp.org]

If a case of PR hasn't cleared within 8-10 weeks, I'll usually perform a workup to verify nothing has been overlooked. Currently, there is no treatment available which clears the rash. [web.archive.org]

In such cases, the patient should urgently visit a hospital for further workup and management usually treated with steroids (topical and oral or systemic) analgesics, immunomodulators and immunosuppressive therapy. [fever.pk]

• Human Herpesvirus 8

  AAT Chuh, PKS Chan and A Lee, The detection of human herpesvirus‐8 DNA in plasma and peripheral blood mononuclear cells in adult patients with pityriasis rosea by polymerase chain reaction, Journal of the European Academy of Dermatology and Venereology [doi.org]

  Pityriasis rosea is not associated with human herpesvirus 7. Arch Dermatol 1999;135:1070-2. 8. Watanabe T, Sugaya M, Nakamura K, Tamaki K. Human herpesvirus 7 and pityriasis rosea. J Invest Dermatol 1999;113:288-9. [ PUBMED ] 9. [dx.doi.org]

  Pityriasis rosea is not associated with human herpesvirus 7. Arch Dermatol. 1999; 135 :1070–2. [ PubMed ] [ Google Scholar ] 8. Watanabe T, Sugaya M, Nakamura K, Tamaki K. Human herpesvirus 7 and pityriasis rosea. [ncbi.nlm.nih.gov]

  Pityriasis rosea is not associated with human herpesvirus 7. Arch Dermatol 1999;135:1070-2. 8. Watanabe T, Sugaya M, Nakamura K, Tamaki K. Human herpesvirus 7 and pityriasis rosea. J Invest Dermatol 1999;113:288-9. 9. [go.gale.com]

We searched PubMed for all reports on randomized controlled trials for the treatment of PR published in the past 30 years. [doi.org]

Treatment may be considered in certain cases, although there is a paucity of medical studies supporting any definitive treatment. However, treatment may be warranted for other conditions that mimic pityriasis rosea. [ncbi.nlm.nih.gov]

[…] cause of the condition is not known, but it is linked to a viral infection Mild cases requires no treatment, although the application of corticosteroids and antihistamines on the rashes can help control itching and redness The disorder has a very good prognosis [dovemed.com]

AFP 2004 ; 69(1) Links: clinical features management prognosis guttate psoriasis [gpnotebook.co.uk]

Etiology Idiopathic A viral etiology is suspected based on the following: Pityriasis rosea can occur in clusters, affecting many people living in the same community. [amboss.com]

Even though PR was first described 200 years ago, the etiology and treatment of this condition is still elusive. [e-ijd.org]

Abstract Pityriasis Circinata is a rare, symptomless, etiologically uncertain disease, but often associated with chronic illness such as Tuberculosis, diseases of uterus and ovaries. [koreamed.org]

"Pityriasis rosea: evidence for and against an infectious etiology." Epidemiology and Infection 132:381-390. Drago F, Broccolo F, Rebora A. 2009. "Pityriasis rosea: an update with a critical appraisal of its possible herpesviral etiology." [pedclerk.bsd.uchicago.edu]

Significantly more parents of children with PR had concerns regarding the etiology, infectivity, relapse, and complications or dangers of the disease. [doi.org]

Epidemiology References:[1] Epidemiological data refers to the US, unless otherwise specified. [amboss.com]

Previously reported virological and epidemiological results for these rashes are conflicting in many aspects. [ncbi.nlm.nih.gov]

Owing to the relatively small number of patients, virological and epidemiology studies, and treatment trials usually recruit few study and control subjects. This leads to low statistical powers and thus results have little clinical significance. [doi.org]

Epidemiology Pityriasis rosea presents most often in patients between the ages of 10 and 35 years of age, though case reports indicate the presence of the disease in patients of all ages. [pedclerk.bsd.uchicago.edu]

Epidemiology PR is universal. [ijdvl.com]

Pathogenesis The pathophysiology of pityriasis rosea is poorly understood. The disease is believed to be viral in origin, given the way in which cases cluster in space and time as well as the low rate of recurrence. [pedclerk.bsd.uchicago.edu]

It affects people of both genders between 15 and 30 years of age, but it also affects older adults and children.[7] Pathophysiology A lack of natural killer (NK) cell and B-cell activity in pityriasis rosea lesions has been noted, suggesting a predominantly [statpearls.com]

Pathophysiology Pityriasis rosea (PR) has often been considered to be a viral exanthem, a view supported by the condition’s seasonal occurrence, its clinical course, the possibility of epidemic occurrence, the presence of occasional prodromal symptoms [emedicine.com]

Can it be prevented or avoided? You cannot prevent or avoid this condition. Treatment Treatment cannot cure pityriasis rosea, but medicine can help relieve the itching. Your doctor may suggest antihistamine pills, such as Benadryl. [news.gcu.edu]

100% Emergent - ED Care Needed - Preventable/Avoidable - 0% Emergent - ED Care Needed - Not Preventable/Avoidable - 0% Primary diagnosis of injury 0% Primary diagnosis of mental health problems 0% Primary diagnosis of substance abuse 0% Primary diagnosis [codelay.com]

Prevention There is no known prevention. There are cases of other family members being affected but it is not considered contagious. [shcs.ucdavis.edu]

Can pityriasis rosea be prevented or avoided? You cannot prevent or avoid this condition. Pityriasis rosea treatment Treatment cannot cure pityriasis rosea, but medicine can help relieve the itching. [familydoctor.org]

Currently, there are no known measures to prevent Atypical Pityriasis Rosea. [dovemed.com]