Presentation
CASE REPORT: We present the case of a 16-year-old male who presented on two separate occasions after a tonic-clonic seizure with hip pain, an antalgic gait, and marked discomfort on hip flexion. [ncbi.nlm.nih.gov]
Entire Body System
- Fatigue
Sick sinus syndrome (SSS) is a dysfunction of sinoatrial node resulting in symptomatic bradycardia or sinus pauses causing decreased cardiac output with cerebral hypoperfusion and usually presents as syncope, presyncope or fatigue. [ncbi.nlm.nih.gov]
When a seizure stops, people may have a headache, sore muscles, unusual sensations, confusion, and profound fatigue. These after-effects are called the post-ictal state. [msdmanuals.com]
The risk of photosensitive epileptic seizures may be reduced by taking the following precautions: Play in a well-lit room Do not play if you’re drowsy or fatigued If you or any of your relatives have a history of seizures or epilepsy, consult a doctor [support.xbox.com]
For the majority of people who have seizures, there's one symptom that follows having a seizure--a very intense feeling of fatigue. [tbiguide.com]
- Family History of Epilepsy
There may be a family history of epilepsy or seizures. If seizures continue repeatedly after the underlying problem is treated, the condition is called epilepsy. Most seizures stop by themselves. [medlineplus.gov]
Risk of future afebrile convulsions (epilepsy) is increased by family history of epilepsy, any neurodevelopmental problem, atypical febrile convulsions (prolonged or focal). [rch.org.au]
history of epilepsy or fever-related seizures Alzheimer's disease (late in the illness) Lengthy fever-related (febrile) seizures Alcohol or drug abuse A doctor makes his or her epilepsy diagnosis based on symptoms, physical signs and the results of such [aans.org]
During the interview a detailed family history searching for epilepsy was obtained as well. [scielo.org.ar]
About 15-40% of patients with these epilepsies have a family history of epilepsy; overall concordance in monozygotic twins is 74%, with a 100% concordance during the peak age of phenotypic expression. [9] Family members may have other forms of idiopathic [reference.medscape.com]
Cardiovascular
- Hypertension
The exposure was defined as a hypertensive disorder of pregnancy, namely 1) eclampsia, 2) preeclampsia, or 3) gestational hypertension. The referent was an unaffected pregnancy. [ncbi.nlm.nih.gov]
Causes of Seizures Causes of Seizures Condition Examples Autoimmune disorders Cerebral vasculitis, anti-NMDA receptor encephalitis, multiple sclerosis (rarely) Cerebral edema Eclampsia, hypertensive encephalopathy Cerebral ischemia or hypoxia Cardiac [msdmanuals.com]
Typical symptoms include the following: Drowsiness Confusion Memory loss Nausea General malaise Body soreness Difficulty finding names or words Headaches/migraines Thirst Arm or leg weakness Hypertension Feelings of fear, embarrassment, or sadness Reviewed [cureepilepsy.org]
Musculoskeletal
- Fracture
KEYWORDS: avulsion fracture; fracture; lesser trochanter; seizure injury [ncbi.nlm.nih.gov]
[…] undergoing any sort of spasm and 3)do not place any body part in-between the person's teeth during a seizure (including your fingers)to stop the chattering and or clenching of teeth, if wanting to protect the subject from injuring themselves (involving fracturing [en.wikipedia.org]
[…] tuberous sclerosis Pressure-related Decompression illness, hyperbaric oxygen treatments Withdrawal syndromes Alcohol, anesthetics, barbiturates, benzodiazepines * Posttraumatic seizures occur in 25 to 75% of patients who have brain contusion, skull fracture [msdmanuals.com]
- Contusion
Neurofibromatosis, tuberous sclerosis Pressure-related Decompression illness, hyperbaric oxygen treatments Withdrawal syndromes Alcohol, anesthetics, barbiturates, benzodiazepines * Posttraumatic seizures occur in 25 to 75% of patients who have brain contusion [msdmanuals.com]
Psychiatrical
- Abnormal Behavior
However, in some children with ASD, subtle symptoms of seizures are very difficult to differentiate from abnormal behaviors commonly associated with ASD, and in other children with ASD, behaviors that appear to be seizure-like are not seizures. [tacanow.org]
Your child may look awake but have a variety of abnormal behaviors. These behaviors may range from gagging, lip smacking, running, screaming, crying, and/or laughing. Children do not remember what they experience during this seizure type. [texaschildrens.org]
Dohan FC, Levitt DR, Kushnir LD: Abnormal behavior after intracerebral injection of polypeptides from wheat gliadin: Possible relevance to schizophrenia. Pavlovian Journal of Biological Science 13:73–82, 1978 PubMed CrossRef Google Scholar 57. [dx.doi.org]
During the seizure, mental processes (including awareness) and/or behavior are affected. People may appear confused or spaced out. They may be unable to speak and may behave irrationally. [msdmanuals.com]
Urogenital
- Uremia
[…] seizures, although they do not have a primarily brain-related cause: Event-related seizures Febrile seizure Withdrawal of alcohol Hypoxia e.g. due to a traumatic brain injury Intoxication Metabolic deviations ( ketoacidosis, hypoglycemia, hypocalcemia, uremia [flexikon.doccheck.com]
Convulsions may be a symptom resulting from various conditions and diseases, such as epilepsy, uremia, eclampsia, rabies, tetanus, strychnine poisoning, and cerebral tumour. They are usually accompanied by loss of consciousness. [britannica.com]
Neurologic
- Convulsions
"Convulse" redirects here. For Finnish death metal band, see Convulse (band). [en.wikipedia.org]
Even if you’ve had convulsions or a seizure or two, it doesn’t necessarily mean you have epilepsy. Fever (febrile convulsion) A convulsion caused by fever is called a febrile convulsion. [healthline.com]
Seizures or Convulsions How you can help 1. [stjohn.org.nz]
Upon completion of the flicker ERG recording, a paralysis developed in both upper limbs, then convulsions of the lower limbs followed by a loss of consciousness. The convulsions disappeared after an intravenous injection of diazepam. [ncbi.nlm.nih.gov]
- Generalized Seizure
They can cause some of the same physical symptoms as a generalized seizure, like convulsions or muscle slackness. [webmd.com]
Generalized Seizures Section Generalized seizures occur when there is widespread seizure activity in the left and right hemispheres of the brain. [epilepsyontario.org]
CONCLUSIONS: Epileptic seizures as one of the clinical manifestations are uncommon. The two most common seizure types were generalized seizures and status epilepticus. [ncbi.nlm.nih.gov]
Generalized Seizures Generalized seizures begin with a widespread, excessive electrical discharge involving both hemispheres, or sides, of the brain. [nyulangone.org]
- Focal Seizure
Focal Seizures Doctors break these into three groups: Simple focal seizures: They change how your senses read the world around you: They can make you smell or taste something strange, and may make your fingers, arms, or legs twitch. [webmd.com]
Focal seizures may also be called partial seizures. With focal seizures, particularly with complex focal seizures, the child may experience an aura before the seizure occurs. [beaumont.org]
There are two types of focal seizures: Focal seizures with retained awareness This type of focal seizure was previously known as a simple partial seizure. [epilepsyontario.org]
Focal seizures Focal seizures occur when one area (or lobe) of the brain is affected by abnormal electrical activity. The symptoms and level of consciousness depend on the area of the brain involved. [youngepilepsy.org.uk]
Focal Seizures Focal seizures begin with an abnormal electrical discharge restricted to one small region of the brain. [nyulangone.org]
- Atonic Seizures
They may start in the same part of the brain as an atonic seizure, and some people have both myoclonic and atonic seizures. Absence (or petit mal) seizures: You seem disconnected from others around you and don’t respond to them. [webmd.com]
[…] awaken Atonic Seizures or Drop Attacks brief seizures, short duration cause an unexpected and rapid fall to the ground can result from tonic (stiffening) or atonic (sudden loss of tone) events difficult to treat high risk of injury Disorders that Mimic [barrowneuro.org]
If this is the first observation of an absence seizure, medical evaluation is recommended. Atonic (also called a drop attack) : Atonic seizures cause loss of muscle tone. In fact, Atonic literally means “without tone” so the muscles become weak. [efepa.org]
Atonic Seizures With atonic seizures in children (also called drop attacks) there is a sudden loss of muscle tone and the child may fall from a standing position or suddenly drop his/her head. During the seizure, the child is limp and unresponsive. [beaumont.org]
- Agitation
English Translation More meanings for Konvulsion Similar Words Katastrophe noun catastrophe, disaster, cataclysm, tragedy Beschlagnahme noun seizure, confiscation, condemnation, impounding, monopolization Agitation noun agitation Turbulenz noun turbulence [wordhippo.com]
Consciousness returns slowly, and the person may be drowsy, confused, agitated, or depressed. [epilepsynewengland.org]
Call your healthcare provider right away if you have any of these symptoms, especially if they are new, worse, or worry you: thoughts about suicide or dying; new or worse depression; feeling agitated or restless; trouble sleeping (insomnia); acting aggressive [fycompa.com]
The most prevalent adverse effects are behavioral, including agitation, aggressive behavior, and mood instability. Levetiracetam has been linked to suicide in a few individuals without ASD. [tacanow.org]
The type and length of aftereffects will vary from person to person and may include: Confusion and agitation Fatigue and drowsiness Headache Loss of bowel or bladder control Loss of consciousness or unresponsiveness Numbness Partial paralysis Exceptional [uchospitals.edu]
Workup
This case report describes the clinical course, workup, and differential diagnosis of a 15-year-old male adolescent with first-time seizure and Brugada pattern on electrocardiogram. A brief review of the literature follows the case presentation. [ncbi.nlm.nih.gov]
Most patients will be admitted to a telemetry floor for close monitoring, further workup, and treatment of their underlying condition. [emedicine.com]
However, every child with ASD and seizures should have a comprehensive medical workup for known medical disorders. [tacanow.org]
EEG
- Epileptiform Activity
Electroencephalogram (EEG) was negative for epileptiform activity. A diagnosis of seizure in the setting of dementia with Lewy bodies (DLB) was deemed probable. [ncbi.nlm.nih.gov]
Temporal epileptiform and nonepileptiform activities, mostly unilateral, were found in both groups. Extratemporal epileptiform activities (frontal, parietal, central, occipital and generalized) were also found equally in both groups. [dx.doi.org]
Since altered awareness occurs with even brief bursts of spike-wave paroxysms on EEG, treatment should be titrated to suppressing all epileptiform activity. The decision to start antiepileptic medication must be made with great care. [reference.medscape.com]
Serum
- Hyponatremia
[…] frequency Expanding intracranial lesions Hemorrhage, hydrocephalus, tumors Hyperpyrexia Drug toxicity (eg, with amphetamines or cocaine), fever, heatstroke Metabolic disturbances Commonly, hypocalcemia (eg, secondary to hypoparathyroidism), hypoglycemia, hyponatremia [msdmanuals.com]
Sometimes seizures happen because of: High fever, which can be associated with an infection such as meningitis Lack of sleep Low blood sodium (hyponatremia), which can happen with diuretic therapy Medications, such as certain pain relievers, antidepressants [mayoclinic.org]
Oxcarbazepine : Hyponatremia (low blood sodium) can develop in some individuals. Topiramate : Common adverse effects include weight loss and cognitive and psychomotor slowing. [tacanow.org]
Treatment
RESULTS: Rapid initiation and escalation of status epilepticus treatment has been associated with shortened seizure duration and more favorable outcomes. [ncbi.nlm.nih.gov]
Prognosis
The current study aimed to perform a comprehensive meta-analysis to investigate the correlation of isocitrate-dehydrogenase 1 (IDH1), an important molecular biomarker for glioma classification and prognosis, to preoperative seizure incidence in LGG. [ncbi.nlm.nih.gov]
The management and prognosis is the same as for classical febrile convulsions. Acute Management Treat the convulsion when necessary as per Convulsions guidelines. * Reassurance is important in simple febrile convulsions. [rch.org.au]
Etiology
The choice of antiepileptic drug is typically based on seizure type, and there is no evidence for superior effectiveness or potential deterioration of particular antiepileptic drug in specific etiologic subgroups. [ncbi.nlm.nih.gov]
In children with TLE of different etiologies there is a wide clinico-electroencephalographic diversity 2,10-13. [dx.doi.org]
Epidemiology
The classification of seizures in old age in epidemiologic studies is rarely satisfactory. [dictionary.cambridge.org]
Epidemiology Age-adjusted incidence of epilepsy in North America ranges between 16/100,000 and 51/100,000 person-years. The age-adjusted prevalence ranges from 2.2/1000 to 41/1000 depending on the country. [ncbi.nlm.nih.gov]
The epidemiology of the epilepsies. Handbook of Clinical Neurology. 107. pp. 113–33. doi:10.1016/B978-0-444-52898-8.00006-9. ISBN 9780444528988. PMID 22938966.; Sander JW, Shorvon SD (1996). "Epidemiology of the epilepsies". [en.wikipedia.org]
Clinical Practice and Epidemiology in Mental Health 5:16, 2009 PubMed CrossRef Google Scholar 30. [dx.doi.org]
Epidemiology Incidence in the United States The incidence of absence seizures in the United States is 1.9-8 cases per 100,000 population. [reference.medscape.com]
Pathophysiology
This case report discusses the pathophysiology of post-ictal desaturations and breathing abnormalities during seizures and their possible association with sudden unexpected death in epilepsy. [ncbi.nlm.nih.gov]
The pathophysiology of focal-onset seizures differs from the mechanisms underlying generalized-onset seizures. [emedicine.medscape.com]
Expression of this gene in the developing brain may help explain an age-related onset and remission in childhood absence epilepsy. [20] Pathophysiology The pathophysiology of absence seizures is not fully understood. [reference.medscape.com]
Prevention
CONCLUSION: Improved preventive care, seizure detection, and rescue medication education may advance pre-hospital management, and we propose the use of acute status epilepticus intervention teams to initiate and incorporate in-hospital interventions as [ncbi.nlm.nih.gov]
Also, preventing seizures prevents the injuries and accidents that may occur because of a seizure. [merckmanuals.com]
The main thing is to prevent them from injuring themselves. Put something soft under their head, remove any sharp or unstable objects from the area and stay with them. There is no danger they will swallow their tongue. [healthdirect.gov.au]